Evidence map›Paper›PMID 35227038›Full record

ArticleTurkish journal of pharmaceutical sciences2022

Ameliorative Potential of Rosuvastatin on Doxorubicin-induced Cardiotoxicity by Modulating Oxidative Damage in Rats

Jayaraman Rajangam, Navaneetha Krishnan, Narahari N Palei, Shvetank Bhatt, Manas Kumar Das, Saumya Das, Krishnapillai Mathusoothanan

Open access · diamondAbstract read
In one paragraph

Article in Turkish journal of pharmaceutical sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Jayaraman RajangamSree Vidyanikethan College of Pharmacy, Department of Pharmacology, Andhra Pradesh, IndiaORCID 0000-0002-6367-0365
Navaneetha KrishnanSree Vidyanikethan College of Pharmacy, Department of Pharmacology, Andhra Pradesh, IndiaORCID 0000-0002-2450-3062
Narahari N PaleiSree Vidyanikethan College of Pharmacy, Department of Pharmaceutics, Andhra Pradesh, IndiaORCID 0000-0002-2041-1849
Shvetank BhattAmity University Amity Institute of Pharmacy, Department of Pharmacology, Madhya Pradesh, IndiaORCID 0000-0001-8696-3462
Manas Kumar DasOrlean College of Pharmacy, Department of Pharmacology, Uttar Pradesh, IndiaORCID 0000-0002-9785-8905
Saumya DasNIET College of Pharmacy, Department of Pharmacology, Uttar Pradesh, IndiaORCID 0000-0002-8531-9963
Krishnapillai MathusoothananGrace College of Pharmacy, Department of Pharmaceutics, Kerala, IndiaORCID 0000-0002-7741-7088
Hindu College of Pharmacy · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: The study aimed to explore the Materials and Methods: Cardiac toxicity was induced by DOXO injection (10 mg/kg, Results: Acute administration of DOXO resulted in a marked rise of cardiac marker enzymes that confirms the myocardial damage compared to control animals whereas administration of ROSS (10 mg/kg, Conclusion: From the results, the acute administration of ROSS showed significant cardioprotective property, which was evidenced by a significant reduction of cardiac and liver marker enzymes along with significant improvement of

Indexed as

antioxidantscardiac markersCardioprotectioncardiotoxicitydoxorubicinrosuvastatin

Identifiers

PMID35227038
PMCPMC8892557
OpenAlexW3153893535

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.