Evidence map›Paper›PMID 35226774›Full record

ArticleNMR in biomedicine2022

Dynamic contrast-enhanced MRI parametric mapping using high spatiotemporal resolution Golden-angle RAdial Sparse Parallel MRI and iterative joint estimation of the arterial input function and pharmacokinetic parameters.

Yousef Mazaheri, Nathanael Kim, Yulia Lakhman, Ramin Jafari, Alberto Vargas, Ricardo Otazo

Abstract read
In one paragraph

Article in NMR in biomedicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Acquisition of KQuantitative imaging in medicine and surgery · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yousef MazaheriDepartment of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Nathanael KimDepartment of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Yulia LakhmanDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Ramin JafariDepartment of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Alberto VargasDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Ricardo OtazoDepartment of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, New York, USA.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
Rapid motion-robust quantitative DCE-MRI for the assessment of gynecologic cancersR01CA244532 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI AKIN, OGUZ, OTAZO, RICARDO · 2020 to 2024
$2.9M
NCI NIH HHS P30 CA008748NCI NIH HHS R01 CA244532
6 · The paper itself

Abstract

The aim of this work is to develop a data-driven quantitative dynamic contrast-enhanced (DCE) MRI technique using Golden-angle RAdial Sparse Parallel (GRASP) MRI with high spatial resolution and high flexible temporal resolution and pharmacokinetic (PK) analysis with an arterial input function (AIF) estimated directly from the data obtained from each patient. DCE-MRI was performed on 13 patients with gynecological malignancy using a 3-T MRI scanner with a single continuous golden-angle stack-of-stars acquisition and image reconstruction with two temporal resolutions, by exploiting a unique feature in GRASP that reconstructs acquired data with user-defined temporal resolution. Joint estimation of the AIF (both AIF shape and delay) and PK parameters was performed with an iterative algorithm that alternates between AIF and PK estimation. Computer simulations were performed to determine the accuracy (expressed as percentage error [PE]) and precision of the estimated parameters. PK parameters (volume transfer constant [K

Indexed as

Contrast MediaMagnetic Resonance ImagingAlgorithmsArteriesHumansImage EnhancementReproducibility of ResultsContrast Mediaarterial input functionbolus arrival timedynamic contrast-enhanced MRIGolden-angle RAdial Sparse Parallel MRItemporal resolution

Identifiers

PMID35226774
PMCPMC9203940

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.