Evidence map›Paper›PMID 35226688›Full record

ArticlePloS one2022

Severe mental illness and pregnancy outcomes in Australia. A population-based study of 595 792 singleton births 2009-2016.

Kristina Edvardsson, Elizabeth Hughes, Beverley Copnell, Ingrid Mogren, Don Vicendese, Richard Gray

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 15 citations in OpenAlex.

  1. Pooled it
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  9. Perinatal outcomes of Aboriginal women with mental health disorders.The Australian and New Zealand journal of psychiatry · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Kristina EdvardssonSchool of Nursing and Midwifery, La Trobe University, Bundoora, VIC, Australia.ORCID 0000-0001-6883-3664
Elizabeth HughesSchool of Nursing and Midwifery, La Trobe University, Bundoora, VIC, Australia.
Beverley CopnellSchool of Nursing and Midwifery, La Trobe University, Bundoora, VIC, Australia.
Ingrid MogrenJudith Lumley Centre, La Trobe University, Bundoora, VIC, Australia.
Don VicendeseThe Department of Mathematics and Statistics, La Trobe University, Bundoora, Victoria, Australia.
Richard GraySchool of Nursing and Midwifery, La Trobe University, Bundoora, VIC, Australia.
La Trobe University · AUThe University of Melbourne · AUUniversity of Leeds · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWomen with Severe Mental Illness (SMI) may have more complex pregnancies and pregnancy outcomes that require different care and management, but this has not been extensively studied. The aim of this study was to explore associations between SMI and adverse maternal and infant outcomes in the state of Victoria, Australia.

methodsOur sample included all reported live singleton births in Victoria 2009-2016 (N = 595 792). Associations between SMI and adverse pregnancy outcomes were explored using Odds Ratios (OR), adjusted for sociodemographic and lifestyle factors, and co-morbidities, including any other mental illness.

resultsOf all singleton births, 2046 (0.34%) were to a mother diagnosed with a SMI. We found evidence of an association between SMI and a range of adverse maternal and infant outcomes. Compared to women without SMI, women with a SMI had higher adjusted odds of being admitted to a High Dependency Unit or Intensive Care Unit (aOR 1.83, 1.37-2.43), having gestational diabetes mellitus (1.57, 1.34-1.84), undergoing an unplanned caesarean section (1.17, 1.02-1.33), induction of labour (1.17, 1.05-1.30) and postpartum haemorrhage (1.15, 1.03-1.29). Newborns of women with SMI had higher adjusted odds of being admitted to Special Care Nursery (aOR 1.61, 1.43-1.80), a low Apgar score at 5 minutes (1.50, 1.19-1.90), preterm birth (1.40, 1.20-1.63), and low birthweight (1.26, 1.06-1.49).

conclusionWomen with SMI are at higher risk for a range of adverse maternal and infant outcomes and are a population that may benefit from targeted early identification and enhanced antenatal care.

Indexed as

Mental DisordersPregnancy ComplicationsPregnancy OutcomeAdultAustraliaCesarean SectionDiabetes, GestationalFemaleHumansInfant, NewbornPregnancyPremature BirthVictoriaYoung Adult

Identifiers

PMID35226688
PMCPMC8884496
OpenAlexW4214521344

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.