SynthesisTrauma, violence & abuse2023
Links of Adversity in Childhood With Mental and Physical Health Outcomes: A Systematic Review of Longitudinal Mediating and Moderating Mechanisms.
Synthesis in Trauma, violence & abuse, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed.
- Does exposure to potentially traumatic events moderate the longitudinal relationship between mental health and problematic media use? Moderated multiple mediation analyses within the ABCD study.European journal of psychotraumatology · 2026Observational
- Predicting mental health trajectories after potentially traumatic events: a machine learning approach.European child & adolescent psychiatry · 2026Article
- Living in the Aftermath: Narratives on the impact of exposure to community and school violence in childhood on mental health and adjustment outcomes in later life.Psychology and psychotherapy · 2026Article
- Association of duration and timing of household dysfunction with aggression: A Taiwan birth cohort study.European child & adolescent psychiatry · 2026Article
- The moderating role of adverse childhood experiences in the relationship between workplace incivility and suboptimal health status among nurses.BMC psychology · 2026Article
- Reconstructing fatherhood after childhood trauma: a phenomenological study of Turkish men.Frontiers in psychology · 2026Article
- Predicting Maltreatment in Adolescents with Mentally Ill Parents: A Random Forest Tree Analysis.Child psychiatry and human development · 2025Article
- Differential effects of childhood maltreatment types and timing on psychopathology in formerly out-of-home placed young adults.European psychiatry : the journal of the Association of European Psychiatrists · 2025Article
- The impact of early childhood adversity on adult cognitive performance: The mediating roles of childhood cognitive ability and educational attainment.Social science & medicine (1982) · 2025Article
- Health as a means to flourishing.European journal of epidemiology · 2025Article
- Molecular insights into trauma: A framework of epigenetic pathways to resilience through intervention.Med (New York, N.Y.) · 2025Review
- Effects of childhood trauma on mental health outcomes, suicide risk factors and stress appraisals in adulthood.PloS one · 2025Article
- Patterns of Adverse Childhood Experiences from a Longitudinal South African Community Sample: A Latent Class Analysis.International journal on child maltreatment : research, policy and practice · 2025Article
- The pernicious role of stress on intergenerational continuity of psychopathology.Development and psychopathology · 2024Article
- The impact of early adversity on later life health, lifestyle, and cognition.BMC public health · 2024Article
- The mediating role of behavioral risk factors in the pathway between childhood disadvantage and adult psychological distress in a Finnish employee cohort.Scientific reports · 2024Article
- Co-design workshops with families experiencing multiple and interacting adversities including parental mental health, substance use, domestic violence, and poverty: intervention principles and insights from mothers, fathers, and young people.Research involvement and engagement · 2024Article
- Impact of Adverse Childhood Experiences in Young Adults and Adults: A Systematic Literature Review.Pediatric reports · 2024Review
- Adverse childhood experiences and crime outcomes in early adulthood: A multi-method approach in a Brazilian birth cohort.Psychiatry research · 2024Article
- Associations Between Early Life Adversity and Youth Psychobiological Outcomes: Dimensional and Person-Centered Approaches.Research on child and adolescent psychopathology · 2023Article
Corrections and comments
- Erratum issued
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Adverse childhood experiences (ACEs) have been associated with causes of early death, addiction, mental illness, and poor health. However, studies investigating underlying mechanisms often rely on cross-sectional data or inappropriate study designs. To prevent the negative sequelae associated with ACEs, it is imperative to understand the mechanisms underlying the prospective relationship. The aim of this present review was to provide a synthesis and critical evaluation of the literature regarding the mechanisms underlying this relationship. A search in SCOPUS, MedLine via Ovid, PsycINFO via Ovid, and Web of Science was performed. Studies that utilised a prospective design assessing ACEs in childhood or adolescence, outcomes in adulthood, and analysed either a mediating or moderating relationship were included, unless the study relied on informant report or official records to assess childhood maltreatment types of ACEs. Twenty-two studies examining a longitudinal mediation or moderation were included in a systematic review. A review of the studies found links to psychopathology, delinquent and problem behaviours, poor physical health, and poor socioeconomic outcomes. A clear image of underlying mechanisms is not forthcoming due to (a) poor study design in relation to assessing longitudinal mechanisms, and (b) heterogeneity in the adversities, mechanisms, and outcomes assessed. Based on the review, several gaps and limitations are highlighted and discussed.
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