Evidence map›Paper›PMID 35226421›Full record

ArticleJournal of Korean medical science2022

Personal Exposure to Total VOC Is Associated With Symptoms of Atopic Dermatitis in Schoolchildren.

Eun Kyo Ha, Ju Hee Kim, Dawon Park, Eun Lee, Seung Won Lee, Hye Mi Jee, Youn Ho Shin, Man Yong Han

Open access · goldAbstract read
In one paragraph

Article in Journal of Korean medical science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Cleaning products and classes associated with poor respiratory health.Environmental science and pollution research international · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 1 country.

Eun Kyo HaDepartment of Pediatrics, Hallym University Kangnam Sacred Heart Hospital, Seoul, Korea.ORCID https://orcid.org/0000-0001-8863-5729
Ju Hee KimDepartment of Pediatrics, Hallym University Kangdong Sacred Heart Hospital, Seoul, Korea.ORCID https://orcid.org/0000-0002-4945-0753
Dawon ParkDepartment of Pediatrics, CHA Bundang Medical Center, CHA University School of Medicine, Seongnam, Korea.ORCID https://orcid.org/0000-0002-9579-9921
Eun LeeDepartment of Pediatrics, Chonnam National University Hospital, Chonnam National University Medical School, Gwangju, Korea.ORCID https://orcid.org/0000-0002-0145-7067
Seung Won LeeDepartment of Data Science, Sejong University College of Software Convergence, Seoul, Korea.ORCID https://orcid.org/0000-0001-5632-5208
Hye Mi JeeDepartment of Pediatrics, CHA Bundang Medical Center, CHA University School of Medicine, Seongnam, Korea.ORCID https://orcid.org/0000-0003-0128-065X
Youn Ho ShinDepartment of Pediatrics, CHA Gangnam Medical Center, CHA University School of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0003-3227-5511
Man Yong HanDepartment of Pediatrics, CHA Bundang Medical Center, CHA University School of Medicine, Seongnam, Korea. drmesh@gmail.com.ORCID https://orcid.org/0000-0002-9077-5779
CHA University Bundang Medical Center · KRCHA University · KRChonnam National University Hospital · KRHallym University · KRHallym University Kangnam Sacred Heart Hospital · KRSejong University · KR

Funding

National Research Foundation of Korea NRF2020R1F1A1076452Seongnam Atopy Project for Children Happiness SAP2017
6 · The paper itself

Abstract

backgroundThe urinary levels of volatile organic compound (VOC) metabolites provide individual exposure levels compared to data obtained by measuring these compounds in ambient air. We aimed to investigate the association between personal urinary concentrations of VOC metabolites and symptoms of atopic dermatitis in schoolchildren.

methodsNine urinary VOC metabolites were analyzed from urine samples of 149 children. Diagnosis of atopic dermatitis was determined using standardized questionnaires. Pediatricians visited the schools and rated the severity of symptoms using the SCORing Atopic Dermatitis (SCORAD) in all children.

resultsForty-five children (30.2%) had atopic dermatitis based on the International Study of Asthma and Allergies in Childhood (ISAAC) results and 35 children (23.8%) had symptoms of atopic dermatitis with positive SCORAD index values (defined as SCORAD ≥ 5). Children with benzylmercapturic acid detected in personal urines were associated with presence of atopic dermatitis and positive SCORAD index values. Children in the highest quartile of mandelic acid concentration were associated with presence of atopic dermatitis and positive SCORAD results.

conclusionPersonal exposure to VOCs, as indicated by urinary levels of VOC metabolites, was associated with presence of atopic dermatitis and the SCORAD index value.

Indexed as

AsthmaDermatitis, AtopicEczemaHypersensitivityVolatile Organic CompoundsChildHumansSeverity of Illness IndexVolatile Organic CompoundsAtopic DermatitisUrinary MetaboliteVolatile Organic Compounds

Identifiers

PMID35226421
PMCPMC8885456
OpenAlexW4213152068

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.