Evidence map›Paper›PMID 35226376›Full record

ArticleThe Laryngoscope2022

Incidental FDG-Avid Focuses in Palatine Tonsils on PET/CT.

Kasper Basse Reinholdt, André Henrique Dias, Camilla Molich Hoff, Lars Christian Gormsen, Tejs Ehlers Klug

Open access · hybridAbstract read
In one paragraph

Article in The Laryngoscope, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Prevalence and malignant risk of incidental uptake in the oropharynx detected by PET-CT: a systematic review and meta-analysis.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025
    Pooled it
  2. Trans-Cervical Ultrasound Imaging of the Adult Palatine Tonsils.Journal of medical radiation sciences · 2026
    Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Kasper Basse ReinholdtDepartment of Otorhinolaryngology, Head and Neck Surgery, Aarhus University Hospital, Aarhus, Denmark.ORCID 0000-0002-3494-278X
André Henrique DiasDepartment of Nuclear Medicine and PET Centre, Aarhus University Hospital, Aarhus, Denmark.
Camilla Molich HoffDepartment of Nuclear Medicine and PET Centre, Aarhus University Hospital, Aarhus, Denmark.
Lars Christian GormsenDepartment of Nuclear Medicine and PET Centre, Aarhus University Hospital, Aarhus, Denmark.
Tejs Ehlers KlugDepartment of Otorhinolaryngology, Head and Neck Surgery, Aarhus University Hospital, Aarhus, Denmark.
Aarhus University Hospital · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe management of incidental findings of FDG-avid tonsils on PET/CT (IFT) is unclear. We aimed to explore the prevalence of malignancy in IFT, identify risk factors for malignancy, and calculate optimal cutoffs of maximum standardized uptake values (SUV

methodsAll patients who were tonsillectomized at our institution because of IFT from October 2011 to December 2020 were included. Patients undergoing PET/CT due to suspected tonsillar disease or cancer of unknown primary were excluded.

resultsIn total, 77 patients were included, of which 11 (14%) of them had IFT malignancy. Dysphagia (p = 0.019) and alcohol abuse (p = 0.035) were associated with malignancy. Absolute SUV

conclusionWe recommend tonsillectomy for patients with IFT displaying SUV LEVEL OF EVIDENCE: 3 Laryngoscope, 132:2370-2378, 2022.

Indexed as

Positron Emission Tomography Computed TomographyTonsillectomyFluorodeoxyglucose F18HumansIncidental FindingsPalatine TonsilPositron-Emission TomographyRadiopharmaceuticalsFluorodeoxyglucose F18RadiopharmaceuticalscancerFDG-PET/CTincidentalmalignancytonsil

Identifiers

PMID35226376
PMCPMC9790499
OpenAlexW4214508402

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.