Evidence map›Paper›PMID 35226132›Full record

ArticleSkeletal radiology2022

Update on MRI findings of osteomyelitis of long bones in the adult population.

Julia Crim, Samantha Salmon, Christy Waranch, Jacob Elfrink, Eleanor Layfield, J Derek Stensby

Abstract read
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In one paragraph

Article in Skeletal radiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Cephalohematoma Infected WithClinical case reports · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Julia CrimUniversity of Missouri at Columbia, 1 Hospital Dr, Columbia, MO, 65212, USA. crimj@health.missouri.edu.ORCID http://orcid.org/0000-0002-4619-5056
Samantha SalmonUniversity of Missouri at Columbia, 1 Hospital Dr, Columbia, MO, 65212, USA.
Christy WaranchUniversity of Missouri at Columbia, 1 Hospital Dr, Columbia, MO, 65212, USA.
Jacob ElfrinkUniversity of Missouri at Columbia, 1 Hospital Dr, Columbia, MO, 65212, USA.
Eleanor LayfieldUniversity of Pennsylvania, Philadelphia, PA, USA.
J Derek StensbyUniversity of Missouri at Columbia, 1 Hospital Dr, Columbia, MO, 65212, USA.
University of Missouri Hospital · USUniversity of Pennsylvania · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo evaluate the usefulness of new and established MRI signs of osteomyelitis in long bones in adults.

methodsAll patient records over a 9-year period with clinical or MRI suspicion for osteomyelitis were retrospectively reviewed, using strict criteria for proof of infection. Two musculoskeletal radiologists independently reviewed the MRIs of proven osteomyelitis.

resultsOut of 45 MRIs of confirmed osteomyelitis, 2 MRIs (4%) did not show confluent low-signal intensity on T1-weighted images, but all showed confluent high-signal intensity on T2-weighted images. Central hypoenhancing regions of marrow without abscess formation were found in 15-18/35 (43-51%) cases where gadolinium was given. We often found multiple foci of marrow replacement in the same bone. The areas of marrow involvement often had an irregular contour. Penumbra sign, marrow fat globules, and sequestra were uncommon.

conclusionMultiple foci of bone marrow signal abnormalities, an irregular contour of marrow abnormality, and central marrow hypoenhancement without abscess are common signs of osteomyelitis of long bones in adults. Confluent low T1-signal intensity is not always present.

Indexed as

AbscessOsteomyelitisAdultGadoliniumHumansMagnetic Resonance ImagingRetrospective StudiesGadoliniumBone infarctHematogenous osteomyelitisMRI of osteomyelitisOsteomyelitisPressure ulcer

Identifiers

PMID35226132
OpenAlexW4214545869

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.