ArticlePlant physiology2022
The bHLH/HLH transcription factors GhFP2 and GhACE1 antagonistically regulate fiber elongation in cotton.
Article in Plant physiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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20 citing papers in PubMed, 52 citations in OpenAlex.
- The mitogen-activated protein kinase GhMPK3 participates in ethylene signaling regulating fiber elongation in cotton (Gossypium hirsutum).Plant cell reports · 2026Article
- Transcriptional and post-transcriptional regulatory networks controlling cotton fibre development.Plant molecular biology · 2026Review
- Transcriptional and post-translational regulation of aquaporins in plants.Stress biology · 2026Review
- GWAS and GS analysis revealed the selection and prediction efficiency for yield, plant morphological, and fiber quality in Gossypium barbadense.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Article
- Genes Affecting Cotton Fiber Length: A Systematic Review and Meta-Analysis.Plants (Basel, Switzerland) · 2025Article
- Potential regulation of cleistogamy in pigeonpea through jasmonic acid and bHLH transcription factor interactions.Plant reproduction · 2025Article
- Cotton GhMAX2 promotes single-celled fiber elongation by releasing the GhS1FA-mediated inhibition of fatty acid biosynthesis.Plant cell reports · 2025Article
- The receptor-like cytoplasmic kinase OsBSK1-2 regulates immunity via an HLH/bHLH complex.Journal of integrative plant biology · 2024Article
- Cotton BOP1 mediates SUMOylation of GhBES1 to regulate fibre development and plant architecture.Plant biotechnology journal · 2024Article
- Simultaneous improvement of fiber yield and quality in upland cotton (Molecular breeding : new strategies in plant improvement · 2024Article
- Strigolactone-induced degradation of SMXL7 and SMXL8 contributes to gibberellin- and auxin-mediated fiber cell elongation in cotton.The Plant cell · 2024Article
- Co-Expression Network Analysis and Introgressive Gene Identification for Fiber Length and Strength Reveal Transcriptional Differences in 15 Cotton Chromosome Substitution Segment Lines and Their Upland and Sea Island Parents.Plants (Basel, Switzerland) · 2024Article
- Cotton BLH1 and KNOX6 antagonistically modulate fiber elongation via regulation of linolenic acid biosynthesis.Plant communications · 2024Article
- mRNA-miRNA analyses reveal the involvement of CsbHLH1 and miR1446a in the regulation of caffeine biosynthesis inHorticulture research · 2024Article
- Seed treatment: an alternative and sustainable approach to cotton seed delinting.Frontiers in bioengineering and biotechnology · 2024Review
- A comprehensive overview of cotton genomics, biotechnology and molecular biological studies.Science China. Life sciences · 2023Review
- AcbHLH144 transcription factor negatively regulates phenolic biosynthesis to modulate pineapple internal browning.Horticulture research · 2023Article
- Brassinosteroids regulate cotton fiber elongation by modulating very-long-chain fatty acid biosynthesis.The Plant cell · 2023Article
- Comprehensive Analysis of the INDETERMINATE DOMAIN (IDD) Gene Family and Their Response to Abiotic Stress inInternational journal of molecular sciences · 2023Article
- Genome-wide identification and characterisation of bHLH transcription factors in Artemisia annua.BMC plant biology · 2023Article
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8 authors at 1 institution in 1 country.
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Abstract
Basic helix-loop-helix/helix-loop-helix (bHLH/HLH) transcription factors play important roles in cell elongation in plants. However, little is known about how bHLH/HLH transcription factors antagonistically regulate fiber elongation in cotton (Gossypium hirsutum). In this study, we report that two bHLH/HLH transcription factors, fiber-related protein 2 (GhFP2) and ACTIVATOR FOR CELL ELONGATION 1 (GhACE1), function in fiber development of cotton. GhFP2 is an atypical bHLH protein without the basic region, and its expression is regulated by brassinosteroid (BR)-related BRASSINAZOLE RESISTANT 1 (GhBZR1). Overexpression of GhFP2 in cotton hindered fiber elongation, resulting in shortened fiber length. In contrast, suppression of GhFP2 expression in cotton promoted fiber development, leading to longer fibers compared with the wild-type. GhFP2 neither contains a DNA-binding domain nor has transcriptional activation activity. Furthermore, we identified GhACE1, a bHLH protein that interacts with GhFP2 and positively regulates fiber elongation. GhACE1 could bind to promoters of plasma membrane intrinsic protein 2;7 (GhPIP2;7) and expansions 8 (GhEXP8) for directly activating their expression, but the interaction between GhFP2 and GhACE1 suppressed transcriptional activation of these target genes by GhACE1. Taken together, our results indicate that GhACE1 promotes fiber elongation by activating expressions of GhPIP2;7 and GhEXP8, but its transcription activation on downstream genes may be obstructed by BR-modulated GhFP2. Thus, our data reveal a key mechanism for fiber cell elongation through a pair of antagonizing HLH/bHLH transcription factors in cotton.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.