Evidence map›Paper›PMID 35225947›Full record

ArticleMedical sciences (Basel, Switzerland)2022

Dynamics in Morbidity Markers and Cytological Observations Made in Urine of

Patience B Tetteh-Quarcoo, Asamoah Ampong, Nicholas T K D Dayie, John Ahenkorah, Emilia A Udofia, Emmanuel Afutu, Robert Aryee, Benjamin P Niriwa, Fleischer C N Kotey, Eric S Donkor and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Medical sciences (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Patience B Tetteh-QuarcooDepartment of Medical Microbiology, University of Ghana Medical School, Accra P.O. Box KB 4236, Ghana.ORCID 0000-0002-3344-4869
Asamoah AmpongDepartment of Medical Microbiology, University of Ghana Medical School, Accra P.O. Box KB 4236, Ghana.
Nicholas T K D DayieDepartment of Medical Microbiology, University of Ghana Medical School, Accra P.O. Box KB 4236, Ghana.
John AhenkorahDepartment of Anatomy, University of Ghana Medical School, Accra P.O. Box KB 4236, Ghana.ORCID 0000-0002-0617-5210
Emilia A UdofiaDepartment of Community Health, University of Ghana Medical School, Accra P.O. Box KB 4236, Ghana.
Emmanuel AfutuDepartment of Medical Microbiology, University of Ghana Medical School, Accra P.O. Box KB 4236, Ghana.
Robert AryeeDepartment of Medical Microbiology, University of Ghana Medical School, Accra P.O. Box KB 4236, Ghana.ORCID 0000-0003-3643-4217
Benjamin P NiriwaDepartment of Medical Microbiology, University of Ghana Medical School, Accra P.O. Box KB 4236, Ghana.ORCID 0000-0003-0946-8833
Fleischer C N KoteyDepartment of Medical Microbiology, University of Ghana Medical School, Accra P.O. Box KB 4236, Ghana.ORCID 0000-0003-0286-3638
Eric S DonkorDepartment of Medical Microbiology, University of Ghana Medical School, Accra P.O. Box KB 4236, Ghana.
Patrick F Ayeh-KumiDepartment of Medical Microbiology, University of Ghana Medical School, Accra P.O. Box KB 4236, Ghana.
University of Ghana · GH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSchistosomiasis is a neglected tropical disease caused by helminths of the genus

aimThe aim of this study was to identify changes/dynamics in morbidity markers and cytological abnormalities in the urine deposits of METHODOLOGY: This was a longitudinal study involving baseline and follow-up sampling among basic school children living in schistosomiasis-endemic communities. Urine samples were collected from 520 children at baseline and examined for

resultsMorbidity markers such as hematuria, proteinuria, and leukocyturia were detected both at baseline and post-treatment among the infected children (30/520). Hematuria was the predominant parameter (90%, 27/30) detected at baseline, followed by proteinuria (53.3%, 16/30). Leukocyturia was the rarest parameter detected at baseline (13.3%, 4/30). However, almost all these parameters declined gradually post-treatment. Regarding cytological analyses, inflammatory cells were observed most (70.0%, 21/30) at baseline. For hyperkeratotic cells and squamous metaplastic cells, 46.7% and 26.7% were respectively observed at baseline, all of which gradually declined during the weekly follow-ups. Notably, squamous metaplastic cells persisted in all the participants from Week 1 through Week 3 post-treatment, but declined gradually thereafter.

conclusionsMorbidity markers and cytological observations in the children gradually decreased after treatment. Therefore, we continue to recommend routine cytological screening for urogenital schistosomiasis patients at hospitals in

Indexed as

Carcinoma, Squamous CellSchistosomiasis haematobiaAnimalsChildFemaleHematuriaHumansLongitudinal StudiesMaleMorbidityPraziquantelProteinuriaSchistosoma haematobiumPraziquantelcytologymicroscopymorbidityschistosomiasisS. haematobium

Identifiers

PMID35225947
PMCPMC8883892
OpenAlexW4213327240

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.