ReviewMedical sciences (Basel, Switzerland)2022
Assessing Fluid Intolerance with Doppler Ultrasonography: A Physiological Framework.
Review in Medical sciences (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed.
- The effect of preload on Doppler systolic time in a large emergency department cohort with suspected sepsis.Intensive care medicine experimental · 2026Article
- Fluids in sepsis.BJA education · 2026Review
- A Guyton-based hypothesis for venous congestion.The ultrasound journal · 2026Article
- The fluid paradox: dissociation between clinical and ultrasound parameters of fluid overload - results of the INCIVEX exploratory study.Anaesthesiology intensive therapy · 2026Observational
- Point-of-care ultrasound in emergency department sepsis and septic shock: a pragmatic framework for source-oriented assessment and physiologic reassessment.Frontiers in medicine · 2026Review
- Echocardiography in the Ventilated Patient: What the Clinician Has to Know.Journal of clinical medicine · 2024Review
- Passive leg raising uncovers venous congestion: dynamic fluid intolerance and the Doppler Starling curve.Critical care (London, England) · 2024Article
- A Multivariate Phenotypical Approach of Sepsis and Septic Shock-A Comprehensive Narrative Literature Review.Medicina (Kaunas, Lithuania) · 2024Review
- Optimising flow without congestion using the venous-arterial Doppler enhanced resuscitation framework.Australasian journal of ultrasound in medicine · 2024Article
- Simultaneous Venous-Arterial Doppler Ultrasound During Early Fluid Resuscitation to Characterize a Novel Doppler Starling Curve: A Prospective Observational Pilot Study.Journal of intensive care medicine · 2024Observational
- The elusive relationship between cardiac filling and fluid responsiveness.Critical care (London, England) · 2024Article
- Challenges in Septic Shock: From New Hemodynamics to Blood Purification Therapies.Journal of personalized medicine · 2024Review
- A nursing-led sepsis response team guiding resuscitation with point-of-care ultrasound: A review and model for improving bundle compliance while individualizing sepsis care.SAGE open medicine · 2024Review
- Point-of-Care Ultrasound-History, Current and Evolving Clinical Concepts in Emergency Medicine.Medicina (Kaunas, Lithuania) · 2023Review
- Inferior Vena Caval Measures Do Not Correlate with Carotid Artery Corrected Flow Time Change Measured Using a Wireless Doppler Patch in Healthy Volunteers.Diagnostics (Basel, Switzerland) · 2023Article
- Unifying Fluid Responsiveness and Tolerance With Physiology: A Dynamic Interpretation of the Diamond-Forrester Classification.Critical care explorations · 2023Article
- Simultaneous venous-arterial Doppler during preload augmentation: illustrating the Doppler Starling curve.The ultrasound journal · 2023Article
- Point-of-Care Ultrasound: A Multimodal Tool for the Management of Sepsis in the Emergency Department.Medicina (Kaunas, Lithuania) · 2023Review
- The effect of gravity-induced preload change on the venous excess ultrasound (VExUS) score and internal jugular vein Doppler in healthy volunteers.Intensive care medicine experimental · 2023Article
- The time cost of physiologically ineffective intravenous fluids in the emergency department: an observational pilot study employing wearable Doppler ultrasound.Journal of intensive care · 2023Article
Corrections and comments
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ultrasonography is becoming the favored hemodynamic monitoring utensil of emergentologists, anesthesiologists and intensivists. While the roles of ultrasound grow and evolve, many clinical applications of ultrasound stem from qualitative, image-based protocols, especially for diagnosing and managing circulatory failure. Often, these algorithms imply or suggest treatment. For example, intravenous fluids are opted for or against based upon ultrasonographic signs of preload and estimation of the left ventricular ejection fraction. Though appealing, image-based algorithms skirt some foundational tenets of cardiac physiology; namely, (1) the relationship between cardiac filling and stroke volume varies considerably in the critically ill, (2) the correlation between cardiac filling and total vascular volume is poor and (3) the ejection fraction is not purely an appraisal of cardiac function but rather a measure of coupling between the ventricle and the arterial load. Therefore, management decisions could be enhanced by quantitative approaches, enabled by Doppler ultrasonography. Both fluid 'responsiveness' and 'tolerance' are evaluated by Doppler ultrasound, but the physiological relationship between these constructs is nebulous. Accordingly, it is argued that the link between them is founded upon the Frank-Starling-Sarnoff relationship and that this framework helps direct future ultrasound protocols, explains seemingly discordant findings and steers new routes of enquiry.
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