ArticleIndian journal of ophthalmology2022
Correlation of vitreous chamber depth with ocular biometry in high axial myopia.
Article in Indian journal of ophthalmology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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11 citing papers in PubMed.
- Splicing variants in MYRF cause partial loss of function in the retinal pigment epithelium leading to nanophthalmos.JCI insight · 2026Article
- Changes in Ocular Biomechanics During Adolescence and Its Relationship with Lifestyle and Myopic Progression: The Oporto Myopia Study.Bioengineering (Basel, Switzerland) · 2026Article
- Vitreous chamber depth as part of axial elongation in pediatric myopia.BMC ophthalmology · 2026Article
- Establishment of a RBL-formula to determine the retinal breaks location for scleral buckling surgery.International ophthalmology · 2025Article
- Longitudinal Study of Changes in Retinal Curvature and its Relationship With Myopia Shift in Chinese Children.Investigative ophthalmology & visual science · 2025Article
- The Ocular Parameter Changes Caused by Reading With Remote Image Optical Screen.Translational vision science & technology · 2025Article
- Updated study on demographic and ocular biometric characteristics of cataract patients indicates new trends in cataract surgery.Scientific reports · 2025Article
- Impact of Refractive Status on Presbyopia Progression among Patients with Presbyopia.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024Observational
- Ocular Biometry Features and Their Relationship with Anterior and Posterior Segment Lengths among a Myopia Population in Northern China.Journal of clinical medicine · 2024Article
- Nonlinear pathological trajectory of a high-myopia C57/BL6J mouse model induced by form deprivation.Frontiers in physiology · 2024Article
- The Effect of Ambient Light Intensity on Transient Changes in Refraction and Ocular Biometric Components following Near Work: A Randomized Clinical Trial.Journal of current ophthalmologyArticle
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6 authors.
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Abstract
purposeThe proportion of axial length (AL) occupied by vitreous chamber depth (VCD), or VCD:AL, consistently correlates to ocular biometry in the general population. Relation of VCD:AL to ocular biometry in high myopia is not known. The purpose of this study is to evaluate the relation of VCD and VCD:AL to ocular biometry of highly myopic eyes.
methodsThis was a cross-sectional retrospective study of records of 214 myopic eyes (<-1 D SE, aged 20-40 years) attending the refractive surgery services. High axial myopia was defined as AL >26.5 mm. Eyes with posterior staphyloma and myopic maculopathy were excluded. Records were assessed for measurements of AL, central corneal thickness (CCT), anterior chamber depth (ACD), lens thickness (LT), white to white diameter (WTW), and vitreous chamber depth (VCD). Groups were formed based on increasing AL, while the sum of CCT, ACD, and LT was recorded as anterior segment depth (AS). The main outcome measure was the correlation of VCD and VCD:AL to ocular biometry. A comparison was also performed based on of degree of axial myopia.
resultsMean age of the patients was 27.0 ± 5.2 years. VCD showed a very strong correlation with AL (R = 0.98, P < 0.001) but did not correlate to any anterior parameter. VCD:AL showed moderate negative relation with AS (R = -0.43, P < 0.001) and ACD (R = -0.3, P < 0.001), while it had a weakly negative relation with LT (R = -0.18, P = 0.006). VCD:AL showed strong negative relation (R > ~0.7) with AS in all individual groups of AL. Among anterior parameters, WTW showed the most consistent relation with ocular biometry.
conclusionVCD:AL is a better correlate of ocular biometry in high myopia as compared to VCD. However, the correlation is weaker than that noted by previous studies done on the general population. Longitudinal studies of VCD:AL in the younger age group is recommended.
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