Evidence map›Paper›PMID 35225539›Full record

Observational studyIndian journal of ophthalmology2022

Epidemic retinitis - Factors associated with poor visual outcomes.

Ankush Kawali, Srinivasan Sanjay, Padmamalini Mahendradas, Ashwin Mohan, Bhujang Shetty

Open access · diamondAbstract readObservational Study
In one paragraph

Observational study in Indian journal of ophthalmology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.8field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Epidemic retinitis during pregnancy.Indian journal of ophthalmology · 2023
    Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Ankush KawaliDepartment of Uveitis and Ocular Immunology, Narayana Nethralaya, Bangalore, Karnataka, India.
Srinivasan SanjayDepartment of Uveitis and Ocular Immunology, Narayana Nethralaya, Bangalore, Karnataka, India.
Padmamalini MahendradasDepartment of Uveitis and Ocular Immunology, Narayana Nethralaya, Bangalore, Karnataka, India.
Ashwin MohanDepartment of Vitreo-retina, Narayana Nethralaya, Bangalore, Karnataka, India.
Bhujang ShettyDepartment of General Ophthalmology, Narayana Nethralaya, Bangalore, Karnataka, India.
Narayana Nethralaya · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo identify factors other than macular edema and retinitis location responsible for poor visual outcomes in epidemic retinitis (ER).

methodsA. retrospective, observational, comparative study. Eyes with corrected distant visual acuity (CDVA) 20/200 or worse at resolution formed Group A. Eyes with central macular thickness (CMT) 600 μm or worse and retinitis within 1500 μm to foveal center at the presentation, but improved to CDVA 20/200 or better at the resolution formed Group B. The patient's history, clinical presentation, imaging, and treatment outcomes were studied and the factors responsible for the final visual outcomes were compared in both groups.

resultsGroups A and B included 25 eyes each. The mean CDVA at the presentation was 20/400 (range: 20/125-20000) and 20/320 (range: 20/80-20000), and mean CMT at the presentation was 948.5 μm (range: 520-1553) and 912.2 μm (range: 615-1250) in Groups A and B, respectively. All eyes except 1 (Group A) had retinitis lesions within 1500 μm of foveal center. The mean CDVA at the resolution was 20/400 (range: 20/200-20/20000) and 20/40 (range: 20/20-20/80) in Groups A and B, respectively. Older age, male gender, diabetic status, delayed presentation, poor presenting CDVA, bilaterality, presence of keratic precipitates, disk pallor, retinal thinning, and subfoveal deposits had a statistically significant association, whereas the absence of skin rash, ellipsoid zone loss, negative WIDAL, Weil-Felix test, and delayed doxycycline therapy or use of steroids without doxycycline had a statistically insignificant association with poor visual outcomes.

conclusionApart from presenting CMT and location of retinitis, multiple demographic, clinical, and imaging factors can be implicated for poor visual outcomes.

Indexed as

Macular EdemaRetinitisFovea CentralisHumansMaleRetrospective StudiesTomography, Optical CoherenceVisual AcuityDoxycyclineepidemic retinitispost-fever retinitistreatmentvisual outcomes

Identifiers

PMID35225539
PMCPMC9114578
OpenAlexW4214575878

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.