Evidence map›Paper›PMID 35225156›Full record

ReviewNeuropsychology, development, and cognition. Section B, Aging, neuropsychology and cognition2022

Remembering past challenges to feel better today: Role of neural dedifferentiation and autobiographical integration in late-life reappraisal.

Bruna Martins-Klein, Irina Orlovsky, Kristin Heideman

Open access · greenAbstract readReview
In one paragraph

Review in Neuropsychology, development, and cognition. Section B, Aging, neuropsychology and cognition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Bruna Martins-KleinDepartment of Psychological and Brain Sciences, University of Massachusetts Amherst, Amherst, MA, USA.
Irina OrlovskyDepartment of Psychological and Brain Sciences, University of Massachusetts Amherst, Amherst, MA, USA.
Kristin HeidemanDepartment of Psychological and Brain Sciences, University of Massachusetts Amherst, Amherst, MA, USA.
University of Massachusetts Amherst · US

Funding

The Role of Autobiographical Memory in Late-Life Emotion RegulationF31AG069409 · NIA · UNIVERSITY OF MASSACHUSETTS AMHERST · PI ORLOVSKY, IRINA · 2020 to 2023
$121k
NIA NIH HHS F31 AG069409
6 · The paper itself

Abstract

Socioemotional theories suggest that surviving a lifetime of life experiences enhances older adult emotional resilience, yet the role of past emotional challenges in current models of emotion regulation is overlooked. In this paper, we propose how integration of memories and hippocampal dedifferentiation may together benefit the reappraisal of novel stressors across the lifespan. First, we review mood benefits of generating positive narratives, and more integrated memories of adverse life events with age. Second, we review neural mechanisms of narrative integration and meaning-making. We propose a framework in which narrative integration and neural dedifferentiation of hippocampal memory representations may facilitate late-life reappraisal via shared positive meaning-making in ventromedial prefrontal cortex (vmPFC). While current evidence supporting this model is limited, we conclude by discussing future directions for testing its components in multivariate neuroimaging studies, and briefly review clinical implications of the proposed model.

Indexed as

Memory, EpisodicAgedEmotionsHippocampusHumansMagnetic Resonance ImagingMental Recallagingautobiographical memoryDedifferentiationemotion regulationintegrationMVPAreappraisal

Identifiers

PMID35225156
PMCPMC9879066
OpenAlexW4214744765

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.