Evidence map›Paper›PMID 35225051›Full record

ReviewIntegrative cancer therapies

Cannabis, Cannabinoids and Cannabis-Based Medicines in Cancer Care.

Donald I Abrams

Open access · goldAbstract readReview
In one paragraph

Review in Integrative cancer therapies. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
7.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 48 citations in OpenAlex.

  1. Reimagining Cannabidiol Delivery Through Carbon Nanodots.Molecules (Basel, Switzerland) · 2026
    Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. State of the Science: Health Care Provider Communication of Cannabis Use Among Adults Living with Cancer.Journal of cancer education : the official journal of the American Association for Cancer Education · 2025
    Review
  8. Review
  9. Article
  10. Article
  11. Adverse events associated with the use of cannabis-based products in people living with cancer: a systematic scoping review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Article
  12. Review
  13. Review
  14. Article
  15. Review
  16. Article
  17. Molecular Advances on Cannabinoid and Endocannabinoid Research.International journal of molecular sciences · 2023
    Article
  18. Cannabis use prevalence, patterns, and reasons for use among patients with cancer and survivors in a state without legal cannabis access.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
    Article
  19. Review
  20. Should oncologists trust cannabinoids?Frontiers in pharmacology · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Donald I AbramsUniversity of California San Francisco, San Francisco, CA, USA.ORCID 0000-0003-2143-6260
University of California, San Francisco · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As medical cannabis becomes legal in more states, cancer patients are increasingly interested in the potential utility of the ancient botanical in their treatment regimen. Although eager to discuss cannabis use with their oncologist, patients often find that their provider reports that they do not have adequate information to be helpful. Oncologists, so dependent on evidence-based data to guide their treatment plans, are dismayed by the lack of published literature on the benefits of medical cannabis. This results largely from the significant barriers that have existed to effectively thwart the ability to conduct trials investigating the potential therapeutic efficacy of the plant. This is a narrative review aimed at clinicians, summarizing cannabis phytochemistry, trials in the areas of nausea and vomiting, appetite, pain and anticancer activity, including assessment of case reports of antitumor use, with reflective assessments of the quality and quantity of evidence. Despite preclinical evidence and social media claims, the utility of cannabis, cannabinoids or cannabis-based medicines in the treatment of cancer remains to be convincingly demonstrated. With an acceptable safety profile, cannabis and its congeners may be useful in managing symptoms related to cancer or its treatment. Further clinical trials should be conducted to evaluate whether the preclinical antitumor effects translate into benefit for cancer patients. Oncologists should familiarize themselves with the available database to be able to better advise their patients on the potential uses of this complementary botanical therapy.

Indexed as

CannabinoidsCannabisMedical MarijuanaNeoplasmsAnalgesicsHumansNauseaVomitingAnalgesicsCannabinoidsMedical Marijuanaantitumor activitycancercannabinoidscannabiscannabis-based medicinesnauseapainsafety concerns

Identifiers

PMID35225051
PMCPMC8882944
OpenAlexW4214752973

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.