ArticleJournal of investigative medicine high impact case reports
Adenovirus Hepatitis in Immunocompetent Adults.
Article in Journal of investigative medicine high impact case reports. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 19 citations in OpenAlex.
- Epstein-Barr virus and hepatic failure: pathogenesis, clinical manifestations, and management.Frontiers in immunology · 2026Review
- Acute hepatitis in a biological male patient secondary to suspected disseminated gonococcal infection in the absence of Fitz-Hugh-Curtis syndrome: a case report.Journal of medical case reports · 2025Article
- Abnormal liver function in children hospitalized with acute respiratory infection of adenoviruses: a retrospective study.Virologica Sinica · 2023Article
- [(Rare) infectious hepatitis as an important differential diagnosis of unclear hepatopathy].Pathologie (Heidelberg, Germany) · 2023Article
- Solved the enigma of pediatric severe acute hepatitis of unknown origin?Frontiers in cellular and infection microbiology · 2023Review
- Severe Acute Hepatitis of Unknown Origin in Children: What Do We Know Today?Journal of clinical and translational hepatology · 2022Review
- Current status of human adenovirus infection in China.World journal of pediatrics : WJP · 2022Review
- Suspected Adenovirus Causing an Emerging HEPATITIS among Children below 10 Years: A Review.Pathogens (Basel, Switzerland) · 2022Review
- [The relationship between adenovirus infection and severe acute hepatitis of unknown etiology].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2022Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A 35-year-old female with no medical history presented with fever. Laboratory work was normal except for elevated liver function test (LFT): alkaline phosphatase (AP) (296), aspartate transaminase (AST) (343), alanine transaminase (ALT) (378), and international normalized ratio (INR) (1.23). Ultrasound liver was normal. Infectious workup was negative for hepatitis A virus (HAV), hepatitis B virus (HBV), hepatitis C virus (HCV), hepatitis E virus (HEV), cytomegalovirus (CMV), Epstein-Barr virus (EBV), Herpes simplex virus (HSV), and COVID-19. Similarly, autoimmune hepatitis, Wilson, and alpha-1 antitrypsin workup were negative. She reported taking Yogi-Kanthika (ayurvedic-proprietary medicine) on/off for seasonal sore throat, yet RUCAM-score was 2 (unlikely a drug induced injury). Respiratory-viral-panel came positive for adenovirus. With supportive treatment, symptoms and LFT trended down, thus, liver biopsy decision was deferred. We believe this is the first reported case of adenovirus hepatitis in an immunocompetent adult. Hence, we suggest that clinicians should consider a refined differential diagnosis for elevated LFT (that includes adenovirus).
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.