Evidence map›Paper›PMID 35225013›Full record

ArticleGlobal spine journal2023

Patterns of Lumbar Spine Malalignment Leading to Revision Surgery for Proximal Junctional Kyphosis: A Cluster Analysis of Over- Versus Under-Correction.

Renaud Lafage, Peter Passias, Basel Sheikh Alshabab, Shay Bess, Justin S Smith, Eric Klineberg, Han Jo Kim, Jonathan Elysee, Christopher Shaffrey, Douglas Burton and 5 more

Open access · goldAbstract read
In one paragraph

Article in Global spine journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Radiographic phenotype-driven clustering in lumbar decompression: comparative study of outcome and reoperation risk.The spine journal : official journal of the North American Spine Society · 2026
    Article
  3. Article
  4. Article
  5. Defining modern iatrogenic flatback syndrome: examination of segmental lordosis in short lumbar fusion patients undergoing thoracolumbar deformity correction.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 8 institutions in 1 country.

Renaud LafageDepartment of Orthopedics, Hospital for Special Surgery, New York, NY, USA.ORCID 0000-0002-4820-1835
Peter PassiasDepartment of Orthopedics, NYU Langone Orthopedic Hospital, New York, NY, USA.
Basel Sheikh AlshababDepartment of Orthopedics, Hospital for Special Surgery, New York, NY, USA.
Shay BessDenver International Spine Center, Presbyterian St Luke's/Rocky Mountain Hospital for Children, Denver, CO, USA.
Justin S SmithDepartment of Neurosurgery, University of Virginia Medical Center, Charlottesville, VA, USA.ORCID 0000-0003-0467-5534
Eric KlinebergDepartment of Orthopaedic Surgery, University of California Davis, Sacramento, CA, USA.
Han Jo KimDepartment of Orthopedics, Hospital for Special Surgery, New York, NY, USA.ORCID 0000-0003-2170-3592
Jonathan ElyseeDepartment of Orthopedics, Hospital for Special Surgery, New York, NY, USA.
Christopher ShaffreyDepartment of Neurosurgery, Duke University Medical Center, Durham, NC, USA.
Douglas BurtonDepartment of Orthopaedics, University of Kansas Medical Center, Kansas City, KS, USA.
Richard HostinDepartment of Orthopaedic Surgery, Baylor Scoliosis Center, Dallas, TX, USA.
Gregory MundisDepartment Of Orthopedics, Scripps Clinic, San Diego, CA, USA.
Frank SchwabDepartment of Orthopedics, Hospital for Special Surgery, New York, NY, USA.
Virginie LafageDepartment of Orthopedics, Hospital for Special Surgery, New York, NY, USA.
International Spine Study GroupInternational Spine Study Group, Denver, CO, USA.
Hospital for Special Surgery · USDuke Medical Center · USNew York University Langone Orthopedic Hospital · USRocky Mountain Hospital for Children · USScripps Clinic · USUniversity of California, Davis · USUniversity of Kansas Medical Center · USUniversity of Virginia Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

STUDY

designRetrospective cohort study.

objectiveInvestigate the patterns of fused lumbar alignment in patients requiring revision surgery for proximal junctional kyphosis (PJK).

methodsFifty patients (67.8 yo, 76% female) with existing thoraco-lumbar fusion (T10/12 to pelvis) and indicated for surgical correction for PJK were included. To investigate patterns of radiographic alignment prior to PJK revision, unsupervised 2-step cluster analysis was run on parameters describing the fused lumbar spine (PI-LL) to identify natural independent groups within the cohort. Clusters were compared in terms of demographics, pre-operative alignment, surgical parameters, and post-operative alignment. Associations between pre- and post-revision PJK angles were investigated using a Pearson correlation analysis.

resultsAnalysis identified 2 distinct patterns: Under-corrected (UC,

conclusionsThis study identified 2 patterns of lumbar malalignment associated with severe PJK: over vs under corrected. Despite the difference in PJK etiology, both patterns underwent the same revision strategy. Future analysis should look at the effect of correcting focal deformity alone vs correcting focal deformity and underlying malalignment simultaneously on recurrent PJK rate.

Indexed as

adult spinal deformityage-adjusted alignmentover-correctionproximal junctional kyphosisunder-correctionunsupervised cluster analysis

Identifiers

PMID35225013
PMCPMC10556910
OpenAlexW4214703095

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.