ArticleHuman brain mapping2022
Decoding task specific and task general functional architectures of the brain.
Article in Human brain mapping, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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6 citing papers in PubMed.
- Introducing Structural Reliance: A New Method to Assess Structure-Function Coupling in the Brain.Human brain mapping · 2026Article
- Influence of cognitive networks and task performance on fMRI-based state classification using DNN models.Scientific reports · 2025Article
- High-accuracy machine learning techniques for functional connectome fingerprinting and cognitive state decoding.Human brain mapping · 2023Article
- TSP-GNN: a novel neuropsychiatric disorder classification framework based on task-specific prior knowledge and graph neural network.Frontiers in neuroscience · 2023Article
- Decoding task specific and task general functional architectures of the brain.Human brain mapping · 2022Article
- Deep learning interpretability in neuroimaging: A comprehensive survey and methodological recommendations.Imaging neuroscience (Cambridge, Mass.)Article
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Authors and funding
3 authors.
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Abstract
Functional magnetic resonance imaging (fMRI) is used to capture complex and dynamic interactions between brain regions while performing tasks. Task related alterations in the brain have been classified as task specific and task general, depending on whether they are particular to a task or common across multiple tasks. Using recent attempts in interpreting deep learning models, we propose an approach to determine both task specific and task general architectures of the functional brain. We demonstrate our methods with a reference-based decoder on deep learning classifiers trained on 12,500 rest and task fMRI samples from the Human Connectome Project (HCP). The decoded task general and task specific motor and language architectures were validated with findings from previous studies. We found that unlike intersubject variability that is characteristic of functional pathology of neurological diseases, a small set of connections are sufficient to delineate the rest and task states. The nodes and connections in the task general architecture could serve as potential disease biomarkers as alterations in task general brain modulations are known to be implicated in several neuropsychiatric disorders.
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