Trial reportClinical oral implants research2022
Maxillary sinus floor augmentation comparing bovine versus porcine bone xenografts mixed with autogenous bone graft. A split-mouth randomized controlled trial.
Trial report in Clinical oral implants research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 17 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Split-mouth Randomized Clinical Study on the Use of Symbios Xenograft for Sinus Floor Elevation
Transcriptome Analysis of Human Bone Regeneration After Using an Anorganic Bovine Bone Graft With or Without a Combination of Polynucleotides and Hyaluronic Acid
Radiographic Assessment of Deproteinized Porcine Versus Bovine Bone Mineral in Sinus Augmentation: A Retrospective Study
Who cites it
17 citing papers in PubMed, 3 syntheses or guidelines pooled it, 37 citations in OpenAlex.
- Comparative evaluation of porcine and bovine bone xenografts in bone grafting: a systematic review and meta-analysis.International journal of implant dentistry · 2025Pooled it
- Efficacy of Different Materials for Maxillary Sinus Floor Augmentation With Lateral Approach. A Systematic Review.Clinical implant dentistry and related research · 2025Pooled it
- The impact of deproteinized bovine bone particle size on histological outcomes in sinus floor elevation: a systematic review and meta-analysis.International journal of implant dentistry · 2023Pooled it
- A Histologic, Histomorphometric, and Immunohistochemical Evaluation of Anorganic Bovine Bone and Injectable Biphasic Calcium Phosphate in Humans: A Randomized Clinical Trial.International journal of molecular sciences · 2023Trial
- Maxillary sinus floor augmentation comparing bovine versus porcine bone xenografts mixed with autogenous bone graft. A split-mouth randomized controlled trial.Clinical oral implants research · 2022Trial
- Comparative Evaluation of Bovine- and Porcine-Derived Xenografts in Rabbit Calvarial and Canine Mandibular Dehiscence Models.Dentistry journal · 2026Article
- Implant rehabilitation of extensive maxillary bone loss secondary to chronic odontogenic sinusitis using a press-fit autogenous ramal block graft: a multidisciplinary staged approach.Journal of the Korean Association of Oral and Maxillofacial Surgeons · 2026Article
- Bone Grafts: Everything You Need to Know.Journal of periodontal research · 2026Review
- Sinus Lift with Collagenated Porcine Xenograft in Severely Atrophic Posterior Maxillae: Case Series with Histologic Correlation and Long-Term Outcomes.Dentistry journal · 2025Article
- Electrospun Poly(L-lactide-co-ε-caprolactone) Nanofibers with Hydroxyapatite Nanoparticles Mimic Cellular Interplay in Bone Regeneration.International journal of molecular sciences · 2025Article
- Clinical Indications and Outcomes of Sinus Floor Augmentation With Bone Substitutes: An Evidence-Based Review.Clinical implant dentistry and related research · 2025Review
- APCs in sinus floor augmentation.Periodontology 2000 · 2025Review
- Review
- Cuttlefish Bone-Derived Calcium Phosphate Bioceramics Have Enhanced Osteogenic Properties.Journal of functional biomaterials · 2024Article
- Autologous leucocyte and platelet rich in fibrin (L-PRF) - is it a competitive solution for bone augmentation in maxillary sinus lift? A 6-month radiological comparison between xenografts and L-PRF.Medicine and pharmacy reports · 2024Article
- A Randomized Clinical Trial Comparing Implants Placed in Two Different Biomaterials Used for Maxillary Sinus Augmentation.Materials (Basel, Switzerland) · 2023Article
- Chitosan nanoparticles for sustained release of metformin and its derived synthetic biopolymer for bone regeneration.Frontiers in bioengineering and biotechnology · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
Abstract
aimTo compare the effectiveness of two xenografts for maxillary sinus floor augmentation in terms of clinical, radiographical, histologic, and molecular outcomes. MATERIALS AND
methodsA split-mouth randomized clinical trial was conducted at the University of Granada. Ten consecutive patients in need of bilateral two-staged maxillary sinus floor augmentation were included. Each patient received both biomaterials (porcine bone mineral and anorganic bovine bone), which were randomly assigned for bilateral sinus augmentation. The maxillary autogenous bone scraped from the sinus access window was mixed with each xenograft at a 20:80 ratio. After a healing period of 6 months, bone biopsies were collected with a trephine during the implant placement in the regenerated area. Histologic, histomorphometrical, immunohistochemical, and molecular outcomes were analyzed. Clinical and radiographical data throughout the treatment phases were also evaluated.
resultsThe resulting anatomic features were similar between both groups. After six months of graft consolidation, the graft resorption rates were similar between both biomaterials. The histologic, histomorphometrical, and immunohistochemical results showed no statistical differences between groups.
conclusionAnorganic bovine bone and porcine bone mineral combined with maxillary autogenous cortical bone show similar biologic and radiologic features in terms of biomaterial resorption, osteoconduction, and osteogenesis when used for maxillary sinus floor augmentation.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.