Evidence map›Paper›PMID 35224743›Full record

ArticleStatistics in medicine2022

Extending the susceptible-exposed-infected-removed (SEIR) model to handle the false negative rate and symptom-based administration of COVID-19 diagnostic tests: SEIR-fansy.

Ritwik Bhaduri, Ritoban Kundu, Soumik Purkayastha, Michael Kleinsasser, Lauren J Beesley, Bhramar Mukherjee, Jyotishka Datta

Abstract read
In one paragraph

Article in Statistics in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  14. How many more? Under-reporting of the COVID-19 deaths in Brazil in 2020.Tropical medicine & international health : TM & IH · 2021
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  17. COVID-19 Pandemic in India: Through the Lens of Modeling.Global health, science and practice · 2021
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Ritwik BhaduriDepartment of Statistics, Harvard University, Cambridge, Massachusetts, USA.
Ritoban KunduDepartment of Biostatistics, University of Michigan, Ann Arbor, Michigan, United States.
Soumik PurkayasthaDepartment of Biostatistics, University of Michigan, Ann Arbor, Michigan, United States.
Michael KleinsasserDepartment of Biostatistics, University of Michigan, Ann Arbor, Michigan, United States.
Lauren J BeesleyDepartment of Biostatistics, University of Michigan, Ann Arbor, Michigan, United States.ORCID 0000-0002-3788-5944
Bhramar MukherjeeDepartment of Biostatistics, University of Michigan, Ann Arbor, Michigan, United States.ORCID 0000-0003-0118-4561
Jyotishka DattaDepartment of Statistics, Virginia Polytechnic Institute and State University, Blacksburg, Virginia, USA.ORCID 0000-0001-5991-5182

Funding

XenograftP30CA046592 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Eric R. Fearon · 1988 to 2026
$178.2M
Statistical and computational methods for rare variant association analysisR01HG008773 · NHGRI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MUKHERJEE, BHRAMAR · 2016 to 2020
$1.9M
NCI NIH HHS P30 CA046592NHGRI NIH HHS 5R01HG008773-05NHGRI NIH HHS R01 HG008773
6 · The paper itself

Abstract

False negative rates of severe acute respiratory coronavirus 2 diagnostic tests, together with selection bias due to prioritized testing can result in inaccurate modeling of COVID-19 transmission dynamics based on reported "case" counts. We propose an extension of the widely used Susceptible-Exposed-Infected-Removed (SEIR) model that accounts for misclassification error and selection bias, and derive an analytic expression for the basic reproduction number

Indexed as

COVID-19Basic Reproduction NumberHumansIndiaPandemicsSARS-CoV-2compartmental modelsinfection fatality ratereproduction numberR package SEIRfansyselection biassensitivityundetected infections

Identifiers

PMID35224743
PMCPMC9035093

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.