ArticleNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2022
Are COVID-19 vaccines safe for people with epilepsy? A cross-sectional study.
Article in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.
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Who cites it
10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 28 citations in OpenAlex.
- Safety of COVID-19 vaccine in patients with epilepsy: a meta-analysis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2023Pooled it
- Should patients with epilepsy be vaccinated against coronavirus disease 2019? A systematic review and meta-analysis.Epilepsy & behavior : E&B · 2022Pooled it
- Central nervous system manifestations following vaccination against COVID-19.Brain, behavior, & immunity - health · 2024Review
- SARS-CoV-2 vaccination in paediatric patients with epilepsy: experience of a tertiary center in Colombia.Revista de neurologia · 2023Article
- Experiences from COVID-19 vaccination in patients with epilepsy.Epilepsia open · 2023Article
- Safety and Tolerability of COVID-19 Vaccine in Children With Epilepsy: A Prospective, Multicenter Study.Pediatric neurology · 2023Article
- Effects of COVID-19 Infection and Vaccines on Patients with Epilepsy: Real-Life Experiences.Noro psikiyatri arsivi · 2023Article
- The effect of COVID-19 vaccination on epileptic seizures in patients with epilepsy: A clinical observation in China.Human vaccines & immunotherapeutics · 2022Observational
- Observational retrospective analysis of vaccination against SARS-CoV-2 and seizures: VACCI-COVID registry.Epilepsy & behavior : E&B · 2022Observational
- Effect of inactivated COVID-19 vaccines on seizure frequency in patients with epilepsy: A multicenter, prospective study.Frontiers in immunology · 2022Article
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCOVID-19 disease was first seen in December 2019 and was declared a pandemic soon after. To fight the pandemic, there is an immense need for effective vaccines. The purposes of our study were to investigate the effect of coronavirus vaccines on seizures in people with epilepsy (PWE) and assess the adverse events of COVID-19 vaccine in PWE.
methodsThis was a cross-sectional study. We included epilepsy patients who got vaccinated with two or three doses at least 1 month earlier. We gathered the data using a standardized form. The form contained questions about patients' demographic features, clinical features, and information about the vaccination and its adverse events. The questionnaire included questions about epilepsy-related adverse events.
resultsWe included 178 people with epilepsy in our study. The frequency of adverse events was lower than clinical studies of the vaccines. The mean number of seizures in the month before the vaccination was 1.62, between the doses was 1.61, and after vaccination was 1.64. There was no significant difference in the number of monthly seizures before the vaccination, the month between the doses, or the month after the vaccination (p = 0.46).
conclusionsThe vaccines under consideration in our study were tolerated well by the epilepsy patients. The vaccines did not affect the monthly number of seizures of the PWE. A small number of patients had more seizures than normal after vaccination. We think that benefits of the vaccines outweigh the slightly increased possibility of having a seizure after vaccination.
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