ArticleArchives of gynecology and obstetrics2022
Comparison of ICSI and conventional IVF in non-male factor patients with less than four oocytes.
Article in Archives of gynecology and obstetrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 16 citations in OpenAlex.
- ICSI shows no advantage over conventional IVF in patients with unexpected low oocyte yield.Annals of medicine · 2026Article
- Conventional in vitro fertilization at the age of fourtiesJournal of the Turkish German Gynecological Association · 2026Article
- Beyond oocyte quantity: the paradoxical role of poor ovarian response in live birth outcomes among endometriosis patients undergoing IVF/ICSI-ET.Journal of assisted reproduction and genetics · 2025Article
- Comparison of the outcomes of patients with non-male factor infertility and poor ovarian response undergoing in vitro fertilization and intracytoplasmic sperm injection.The Journal of international medical research · 2025Article
- Insemination methods for embryos transferred in frozen-thawed embryo transfer cycles do not impact reproductive outcomes in couples with non-male factor infertility.Scientific reports · 2025Article
- Comparison of conventional ICSI and rescue ICSI in patients without severe male factor and poor oocyte yield.Frontiers in endocrinology · 2025Article
- The impact of intracytoplasmic sperm injection versus conventional in vitro fertilization on the reproductive outcomes of couples with non-male factor infertility and frozen-thawed embryo transfer cycles.Scientific reports · 2024Article
- Reproductive Outcomes of Conventional In Vitro Fertilization and Intracytoplasmic Sperm Injection in Patients with Non-Severe Male Infertility Across Poor and Different Sub-Optimal Ovarian Response Categories: A Cohort Study Based on 30,352 Fresh Cycles from 2009-2019.Reproductive sciences (Thousand Oaks, Calif.) · 2024Article
- Total Fertilization Failure: A Single Center Analysis.Reproductive sciences (Thousand Oaks, Calif.) · 2024Article
- Impaired embryo development potential associated with thyroid autoimmunity in euthyroid infertile women with diminished ovarian reserve.Frontiers in endocrinology · 2024Article
- Comparisons of conventional in vitro fertilization versus intracytoplasmic sperm injection in women with thyroid autoimmunity and non-male factor infertility, a propensity score matching analysis.Scientific reports · 2023Article
- Opportunities and Limits of Conventional IVF versus ICSI: It Is Time to Come off the Fence.Journal of clinical medicine · 2022Review
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWe aimed to analyse our clinical results for a particular subgroup of patients with poor ovarian response (POR) to clarify if lower number of oocytes is a drawback for proceeding to C-IVF. MATERIALS AND
methodsIn this retrospective study, patient files of all couples (#1733) who underwent oocyte retrieval between January 2017 and December 2019 were reviewed and 191 cases diagnosed with non-male factor infertility in which ≤ 3 cumulus-oocyte complexes available for fertilisation were analysed. Exclusion criteria were: woman age > 42, patients with a history of previous ART trial, prenatal genetic testing cycles and couples undergoing total cryopreservation for any indication. Three groups were constructed depending on the method of fertilisation and on semen quality as follows: IVF non-male factor (Group 1, n = 77); ICSI non-male factor (Group 2, n = 65); ICSI male factor-ICSI/MF n = 49 according to WHO reference values. Main outcome parameters were: fertilisation rate, implantation rate and live birth rate.
resultsFertilisation rate per collected COC was significantly higher in group 1 compared to the other two groups (85.68%, 72.58%, 73.33% respectively, p = 0.004). FR per inseminated oocyte also tended to be higher in group 1 but not reaching a statistically significant level. Both techniques yielded similar implantation rates (20.42%, 28.49%, 23.33% respectively, p = 0.407) and live birth rates (26.8%, 30.6%, 31.1%, respectively, p = 0.643).
conclusionIn the presence of normal semen parameters, low egg number is not an indication to perform ICSI. The choice of fertilisation method should be based primarily on semen quality, in combination with the patient's previous history regardless of the ovarian reserve.
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