Evidence map›Paper›PMID 35224646›Full record

ArticleActa orthopaedica2022

Low incidence of clinically relevant bleeding complications after fast-track arthroplasty: a register study of 8,511 arthroplasties.

Annette Moisander, Konsta Pamilo, Antti Eskelinen, Jukka Huopio, Hannu Kautiainen, Anne Kuitunen, Pirjo Mustonen, Juha Paloneva

Abstract read
In one paragraph

Article in Acta orthopaedica, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Annette MoisanderDepartment of Anesthesia and Intensive Care, Hospital Nova, Central Finland Healthcare District, Jyväskylä. annette.moisander@ksshp.fi.
Konsta PamiloCoxa Hospital for Joint Replacement, Tampere. konsta.pamilo@kolumbus.fi.
Antti EskelinenCoxa Hospital for Joint Replacement, Tampere; Faculty of Medicine and Health Technologies, University of Tampere, Tampere. antti.eskelinen@coxa.fi.
Jukka HuopioDepartment of Orthopaedics and Traumatology, University Hospital, Kuopio. Jukka.Huopio@kuh.fi.
Hannu KautiainenPrimary Health Care Unit, Kuopio University Hospital, Finland, Folkhälsan Research Center, Helsinki. hannu.kautiainen@medcare.fi.
Anne KuitunenDepartment of Intensive Care, University of Tampere, Tampere University Hospital, Tampere. anne.kuitunen@pshp.fi.
Pirjo MustonenTurku University Hospital, Turku. pirjo.mustonen@tyks.fi.
Juha PalonevaDepartment of Surgery, Hospital Nova, Central Finland Healthcare District, Jyväskylä, Finland. juha.paloneva@ksshp.fi.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeFast-track total joint replacement (TJR) has become increasingly common. Routine thromboprophylaxis for pulmonary embolism and deep venous thrombosis prevention lasts from 2 to 5 weeks. This retrospective registry study focused on clinically relevant bleeding complications 90 days after fast-track primary TJR. PATIENTS AND

methodsAll primary fast-track total hip (THA) and knee arthroplasties (TKA) performed between 2015 and 2016 were extracted from the Finnish Arthroplasty Register and Finnish Hospital Discharge Register. Type of arthroplasty and indication for the operation were combined with diagnoses of clinically relevant bleeding complications within 90 days of surgery. The incidence of these bleedings was the primary outcome measure.

resultsOf the total of 8,511 patients (mean age 67 years (SD 10); 60% female), 45% underwent unilateral THA, 52% unilateral TKA, and 3% bilateral TKA. The incidence of clinically relevant bleeding complications within 90 days was 1% (95% CI 0.8-1.3). No difference was observed in bleeding incidence between the groups. The 87 bleedings comprised 57 operative site bleedings, 17 gastrointestinal bleedings, 6 intracranial non-traumatic bleedings, 5 bleedings from the nose or another undetermined site, and 2 intraocular bleedings. 1 death due to intracranial bleeding was recorded, and hence clinically relevant bleeding-specific 90-day mortality was 0.01%.

interpretationThe incidence of clinically relevant bleeding complications was low. However, they cause patient discomfort, increase the use of healthcare services, and can be life-threatening and even fatal.

Indexed as

Arthroplasty, Replacement, HipVenous ThromboembolismAgedAnticoagulantsFemaleHumansIncidenceMalePostoperative ComplicationsRetrospective StudiesAnticoagulants

Identifiers

PMID35224646
PMCPMC8879163

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