Evidence map›Paper›PMID 35224534›Full record

ArticleFrontiers in digital health2021

The Joint Effects of Acoustic and Linguistic Markers for Early Identification of Mild Cognitive Impairment.

Fengyi Tang, Jun Chen, Hiroko H Dodge, Jiayu Zhou

Registry-linked trialAbstract read
In one paragraph

Article in Frontiers in digital health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02871921 (Internet-based Conversational Engagement Clinical Trial), which is not on this map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02871921 nacompletednot on this map

Internet-based Conversational Engagement Clinical Trial

TypeinterventionalSponsorMassachusetts General HospitalRan2018 to 2021Enrolled186ConditionsAging, Mild Cognitive ImpairmentArmsConversational Engagement
3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Speech Acoustic Markers Can Detect Mild Cognitive Impairment in Parkinson's Disease.IEEE journal of selected topics in signal processing · 2025
    Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Detection of Mild Cognitive Impairment from Language Markers with Crossmodal Augmentation.Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing · 2023
    Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Fengyi TangDepartment of Computer Science of Engineering, Michigan State University, East Lansing, MI, United States.
Jun ChenDepartment of Bioinformatics, University of Michigan, Ann Arbor, MI, United States.
Hiroko H DodgeDepartment of Neurology, Layton Aging and Alzheimer's Disease Center, Oregon Health & Science University, Portland, OR, United States.
Jiayu ZhouDepartment of Computer Science of Engineering, Michigan State University, East Lansing, MI, United States.

Funding

Research Education ComponentP30AG066518 · NIA · OREGON HEALTH & SCIENCE UNIVERSITY · PI KEVIN M DUFF, Lisa C Silbert · 2020 to 2026
$28.6M
Identification of Mild Cognitive Impairment using Machine Learning from Language and Behavior MarkersRF1AG072449 · NIA · MICHIGAN STATE UNIVERSITY · PI DODGE, HIROKO HAYAMA, WANG, FEI · 2021 to 2023
$2.6M
NIA NIH HHS P30 AG066518NIA NIH HHS RF1 AG072449
6 · The paper itself

Abstract

In recent years, behavioral markers such as spoken language and lexical preferences have been studied in the early detection of mild cognitive impairment (MCI) using conversations. While the combination of linguistic and acoustic signals have been shown to be effective in detecting MCI, they have generally been restricted to structured conversations in which the interviewee responds to fixed prompts. In this study, we show that linguistic and acoustic features can be combined synergistically to identify MCI in semi-structured conversations. Using conversational data from an on-going clinical trial (Clinicaltrials.gov: NCT02871921), we find that the combination of linguistic and acoustic features on semi-structured conversations achieves a mean AUC of 82.7, significantly (

Indexed as

Alzheimer's diseaseaudio and linguistic markersbehavioral interventionconversationsI-CONECT projectmild cognitive impairment (MCI)

Identifiers

PMID35224534
PMCPMC8878676

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.