ArticleJB & JS open access
Shoulder Periprosthetic Joint Infection and All-Cause Mortality: A Worrisome Association.
Article in JB & JS open access. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Successful glenoid defect management with antibiotic-eluting bone graft substitute following baseplate removal in two-stage revision reverse shoulder arthroplasty: a case report and surgical considerations.JSES reviews, reports, and techniques · 2026Article
- Pre-operative methicillin-resistantJournal of shoulder and elbow arthroplasty · 2026Article
- Does fluid irrigation in arthroscopic shoulder biopsy affect sensitivity ofJSES international · 2025Article
- Factors influencing recurrence rates and radiological outcomes after two-stage exchange arthroplasty for prosthetic joint infection utilizing a premade antibiotic loaded cement hemiarthroplasty.JSES international · 2025Article
- Patient and Surgeon Variables Associated With a Diagnosis of Shoulder Periprosthetic Joint Infection.The archives of bone and joint surgery · 2025Article
- How is infection diagnostic criteria for shoulder periprosthetic joint infection reported in literature: systematic review.JSES international · 2025Review
- The value of an open biopsy in the diagnosis of periprosthetic joint infection.JSES international · 2024Article
- Fungal Shoulder Periprosthetic Infections: A Systematic Review.Journal of clinical medicine · 2024Review
- The effect of allergies on outcomes following shoulder arthroplasty: A national database analysis of 154,478 patients.Shoulder & elbow · 2024Article
- One- vs. Two-Stage Revision for Periprosthetic Shoulder Infections: A Systematic Review and Meta-Analysis.Antibiotics (Basel, Switzerland) · 2024Review
- Infected Shoulder Arthroplasty in Patients Younger than 60 Years: Results of a Multicenter Study.Microorganisms · 2023Article
- Pre-operative corticosteroid injection within 1 month of total shoulder arthroplasty is associated with increased risk of periprosthetic joint infection.Archives of orthopaedic and trauma surgery · 2023Article
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPeriprosthetic joint infection (PJI) can be a devastating complication following shoulder arthroplasty. PJI following hip and knee arthroplasties has been found to increase mortality. However, anatomical and bacteriologic differences could potentially result in a different trend after shoulder arthroplasties. Thus, the purpose of the present study was to determine whether there is an association between shoulder PJI and all-cause mortality.
methodsOur institutional Total Joint Registry Database was queried to identify patients who underwent revision shoulder arthroplasty procedures between 2000 and 2018. A total of 1,160 procedures were then classified as either septic (21.8%) or aseptic (78.2%). Septic revisions were further subdivided into (1) debridement, antibiotics, irrigation, and implant retention (9.1%); (2) 2-stage reimplantation for deep infection (61.3%); (3) implant resection without reimplantation (3.6%); and (4) unexpected positive cultures at revision surgery (26.1%). The most common bacterium isolated was
resultsThe 1-year crude mortality rate was 1.8% (95% confidence interval [CI], 0.9% to 2.6%) for the aseptic group and 2.8% (95% CI, 0.7% to 4.8%) for the septic group (p = 0.31). Multivariate Cox regression analysis demonstrated an elevated but statistically similar adjusted hazard ratio for 1-year all-cause mortality of 1.9 (95% CI, 0.8 to 4.6) when comparing the septic to the aseptic group (p = 0.17). The risk of 2-year all-cause mortality was significantly higher in the septic group, with a hazard ratio of 2.2 (95% CI, 1.1 to 4.5; p = 0.029). In univariate analyses, increased 5-year mortality in the septic revision group was associated with age, Charlson Comorbidity Index, and methicillin-resistant
conclusionsShoulder PJI is associated with an adjusted 2-year all-cause mortality rate that is double that of aseptic patients. The results of the present study should be utilized to appropriately counsel patients who are considered to be at risk for infection following shoulder arthroplasty. LEVEL OF EVIDENCE: Prognostic Level III. See Instructions for Authors for a complete description of levels of evidence.
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