Evidence map›Paper›PMID 35224361›Full record

ArticleACS omega2022

Simple, Sensitive, and Rapid Voltammetric Detection of Alloxan on Glassy Carbon Electrodes.

Mallappa Mahanthappa, Venkatesan Manju, Anugraha Madamangalam Gopi, Palaniappan Arumugam

Open access · goldAbstract read
In one paragraph

Article in ACS omega, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Experimental models in diabetes research.Laboratory animal research · 2026
    Review
  3. Evaluation of Antidiabetic Activity of Oxadiazole Derivative in Rats.Evidence-based complementary and alternative medicine : eCAM · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Mallappa MahanthappaElectrodics and Electrocatalysis Division, CSIR-Central Electrochemical Research Institute (CSIR-CECRI), Karaikudi 630003, India.
Venkatesan ManjuElectrodics and Electrocatalysis Division, CSIR-Central Electrochemical Research Institute (CSIR-CECRI), Karaikudi 630003, India.
Anugraha Madamangalam GopiPG & Research, Department of Chemistry, Sree Vyasa NSS College, Wadakkanchery, Thrissur, Kerala 680582, India.
Palaniappan ArumugamElectrodics and Electrocatalysis Division, CSIR-Central Electrochemical Research Institute (CSIR-CECRI), Karaikudi 630003, India.ORCID https://orcid.org/0000-0003-3503-4852
Central Electrochemical Research Institute · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alloxan is a chemical generally administered to rats to induce diabetes mellitus, and pharmaceutical industries test the efficacy of their diabetic products on these rats. Alloxan is in a redox cycle with dialuric acid; hence, direct estimation of alloxan may not represent the actual concentration of the same in a given matrix. Also, in recent times, alloxan is added to food materials, especially to the all-purpose flour (maida) to bring softness and white color to the flour. Hence, consumption of food items made from such flour could induce diabetic mellitus in individuals, making it imperative to develop an accurate estimation of alloxan in food items. Herein, a voltammetric-based technique is developed to quantify the alloxan in refined wheat flour (maida) using an unmodified glassy carbon electrode (GCE). The electrochemical method offers rapid sensing while the use of an unmodified GCE surface offers repeatability and reproducibility between measurements. First, alloxan is converted to its stable adduct alloxazine by the reaction with

Identifiers

PMID35224361
PMCPMC8867568
OpenAlexW4211221494

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.