Evidence map›Paper›PMID 35224292›Full record

ArticleBioactive materials2022

Oxygen generating scaffolds regenerate critical size bone defects.

Sanika Suvarnapathaki, Xinchen Wu, Tengfei Zhang, Michelle A Nguyen, Anastasia A Goulopoulos, Bin Wu, Gulden Camci-Unal

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bioactive materials, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sanika SuvarnapathakiBiomedical Engineering and Biotechnology Program, University of Massachusetts Lowell, One University Avenue, Lowell, MA, 01854, USA.
Xinchen WuBiomedical Engineering and Biotechnology Program, University of Massachusetts Lowell, One University Avenue, Lowell, MA, 01854, USA.
Tengfei ZhangDepartment of Neurosurgery, Sanbo Brain Hospital, Capital Medicine University, Beijing, 100069, China.
Michelle A NguyenDepartment of Chemical Engineering, University of Massachusetts Lowell, One University Avenue, Lowell, MA, 01854, USA.
Anastasia A GoulopoulosDepartment of Chemical Engineering, University of Massachusetts Lowell, One University Avenue, Lowell, MA, 01854, USA.
Bin WuDepartment of Neurosurgery, Sanbo Brain Hospital, Capital Medicine University, Beijing, 100069, China.
Gulden Camci-UnalDepartment of Chemical Engineering, University of Massachusetts Lowell, One University Avenue, Lowell, MA, 01854, USA.

Funding

Scaffolds with high oxygen content for mineralizationR01DE030129 · NIDCR · UNIVERSITY OF MASSACHUSETTS LOWELL · PI CAMCI-UNAL, GULDEN · 2021 to 2025
$2.0M
NIDCR NIH HHS R01 DE030129
6 · The paper itself

Abstract

Recent innovations in bone tissue engineering have introduced biomaterials that generate oxygen to substitute vasculature. This strategy provides the immediate oxygen required for tissue viability and graft maturation. Here we demonstrate a novel oxygen-generating tissue scaffold with predictable oxygen release kinetics and modular material properties. These hydrogel scaffolds were reinforced with microparticles comprised of emulsified calcium peroxide (CaO

Indexed as

BoneCalcium peroxideCranial regenerationCritical size defectOxygen

Identifiers

PMID35224292
PMCPMC8843972

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.