Evidence map›Paper›PMID 35224122›Full record

ReviewOrthopaedic journal of sports medicine2022

Sex-Specific Outcomes After Anterior Cruciate Ligament Reconstruction: A Systematic Review and Meta-analysis.

Anthony C Mok, Andrew J Fancher, Matthew L Vopat, Jordan Baker, Armin Tarakemeh, Scott Mullen, John P Schroeppel, Kim Templeton, Mary K Mulcahey, Bryan G Vopat

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Orthopaedic journal of sports medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Anthony C MokUniversity of Kansas School of Medicine, Kansas City, Kansas, USA.
Andrew J FancherUniversity of Kansas School of Medicine, Kansas City, Kansas, USA.
Matthew L VopatDepartment of Orthopaedics, The Steadman Clinic, Vail, Colorado, USA.
Jordan BakerUniversity of Kansas School of Medicine, Kansas City, Kansas, USA.
Armin TarakemehDepartment of Orthopaedics, University of Kansas School of Medicine, Kansas City, Kansas, USA.
Scott MullenDepartment of Orthopaedics, University of Kansas School of Medicine, Kansas City, Kansas, USA.
John P SchroeppelDepartment of Orthopaedics, University of Kansas School of Medicine, Kansas City, Kansas, USA.
Kim TempletonDepartment of Orthopaedics, University of Kansas School of Medicine, Kansas City, Kansas, USA.
Mary K MulcaheyDepartment of Orthopaedics, Tulane University, New Orleans, Louisiana, USA.
Bryan G VopatDepartment of Orthopaedics, University of Kansas School of Medicine, Kansas City, Kansas, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDespite the significant difference between men and women in incidence of anterior cruciate ligament (ACL) injuries, there is a paucity of consistent information on the influence of patient sex on outcomes after ACL reconstruction. A previous meta-analysis has demonstrated that female patients have worse outcomes with regard to laxity, revision rate, Lysholm score, and Tegner activity score and are less likely to return to sports (RTS). PURPOSE: To conduct a systematic review and meta-analysis to evaluate and compare sex-specific outcomes after ACL reconstruction. STUDY

designSystematic review; Level of evidence, 4.

methodsA systematic review was performed using PubMed, PubMed Central, Embase, OVID, and Cochrane databases per PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines. The following search terms were used: "anterior cruciate ligament reconstruction" OR "ACL reconstruction" OR "anterior cruciate ligament" OR "ACL" AND "gender" OR "sex" OR "male" OR "female" AND "outcome" AND "2015-Present" to gather all relevant articles between 2015 and 2020. A risk-of-bias assessment and quality assessment was conducted on included studies.

resultsOf 9594 studies initially identified, 20 studies with 35,935 male and 21,455 female patients were included for analysis. The 7 studies reporting International Knee Documentation Committee (IKDC) scores showed that male patients had statistically significantly higher postoperative scores (mean difference, 3.02 [95% CI, 1.19-4.84];

conclusionMale and female patients with ACL injuries demonstrated similar outcomes regarding their rates of revision; however, male patients were found to have statistically significantly higher postoperative IKDC scores but at the same time higher rerupture rates. Our findings suggest that sex-based differences in outcomes after ACL reconstruction vary based on which metric is used. These results must be considered when counseling patients with ACL injuries.

Indexed as

ACLkneeoutcomessexsurgical repair

Identifiers

PMID35224122
PMCPMC8873558

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.