Evidence map›Paper›PMID 35224094›Full record

ArticleBioMed research international2022

TCMPR: TCM Prescription Recommendation Based on Subnetwork Term Mapping and Deep Learning.

Xin Dong, Yi Zheng, Zixin Shu, Kai Chang, Jianan Xia, Qiang Zhu, Kunyu Zhong, Xinyan Wang, Kuo Yang, Xuezhong Zhou

Abstract read
In one paragraph

Article in BioMed research international, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Xin DongInstitute of Medical Intelligence, School of Computer and Information Technology, Beijing Jiaotong University, Beijing 100044, China.ORCID https://orcid.org/0000-0002-1414-9354
Yi ZhengInstitute of Medical Intelligence, School of Computer and Information Technology, Beijing Jiaotong University, Beijing 100044, China.
Zixin ShuInstitute of Medical Intelligence, School of Computer and Information Technology, Beijing Jiaotong University, Beijing 100044, China.
Kai ChangInstitute of Medical Intelligence, School of Computer and Information Technology, Beijing Jiaotong University, Beijing 100044, China.
Jianan XiaInstitute of Medical Intelligence, School of Computer and Information Technology, Beijing Jiaotong University, Beijing 100044, China.ORCID https://orcid.org/0000-0002-4219-0602
Qiang ZhuInstitute of Medical Intelligence, School of Computer and Information Technology, Beijing Jiaotong University, Beijing 100044, China.
Kunyu ZhongInstitute of Medical Intelligence, School of Computer and Information Technology, Beijing Jiaotong University, Beijing 100044, China.
Xinyan WangInstitute of Medical Intelligence, School of Computer and Information Technology, Beijing Jiaotong University, Beijing 100044, China.
Kuo YangInstitute of Medical Intelligence, School of Computer and Information Technology, Beijing Jiaotong University, Beijing 100044, China.ORCID https://orcid.org/0000-0003-0736-4512
Xuezhong ZhouInstitute of Medical Intelligence, School of Computer and Information Technology, Beijing Jiaotong University, Beijing 100044, China.ORCID https://orcid.org/0000-0002-4713-3594

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Traditional Chinese medicine (TCM) has played an indispensable role in clinical diagnosis and treatment. Based on a patient's symptom phenotypes, computation-based prescription recommendation methods can recommend personalized TCM prescription using machine learning and artificial intelligence technologies. However, owing to the complexity and individuation of a patient's clinical phenotypes, current prescription recommendation methods cannot obtain good performance. Meanwhile, it is very difficult to conduct effective representation for unrecorded symptom terms in an existing knowledge base. In this study, we proposed a subnetwork-based symptom term mapping method (SSTM) and constructed a SSTM-based TCM prescription recommendation method (termed TCMPR). Our SSTM can extract the subnetwork structure between symptoms from a knowledge network to effectively represent the embedding features of clinical symptom terms (especially the unrecorded terms). The experimental results showed that our method performs better than state-of-the-art methods. In addition, the comprehensive experiments of TCMPR with different hyperparameters (i.e., feature embedding, feature dimension, subnetwork filter threshold, and feature fusion) demonstrate that our method has high performance on TCM prescription recommendation and potentially promote clinical diagnosis and treatment of TCM precision medicine.

Indexed as

Deep LearningMedicine, Chinese TraditionalPrecision MedicineDrugs, Chinese HerbalHumansPhenotypeDrugs, Chinese Herbal

Identifiers

PMID35224094
PMCPMC8872682

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.