Evidence map›Paper›PMID 35224058›Full record

ArticleFrontiers in cardiovascular medicine2022

Short-Term Supplementation With Fermented Red Clover Extract Reduces Vascular Inflammation in Early Post-menopausal Women.

Kate A Wickham, Line B Nørregaard, Mikkel Oxfeldt, Stephen S Cheung, Lasse Gliemann, Mette Hansen, Ylva Hellsten

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cardiovascular medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Kate A WickhamDepartment of Nutrition, Exercise and Sports, University of Copenhagen, Copenhagen, Denmark.
Line B NørregaardDepartment of Nutrition, Exercise and Sports, University of Copenhagen, Copenhagen, Denmark.
Mikkel OxfeldtDepartment of Public Health, Aarhus University, Aarhus, Denmark.
Stephen S CheungEnvironmental Ergonomics Lab, Faculty of Applied Health Sciences, Brock University, St. Catharines, ON, Canada.
Lasse GliemannDepartment of Nutrition, Exercise and Sports, University of Copenhagen, Copenhagen, Denmark.
Mette HansenDepartment of Public Health, Aarhus University, Aarhus, Denmark.
Ylva HellstenDepartment of Nutrition, Exercise and Sports, University of Copenhagen, Copenhagen, Denmark.
University of Copenhagen · DKAarhus University · DKBrock University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The decline in estrogen at menopause poses a critical challenge to cardiovascular and metabolic health. Recently, a growing interest in the role of phytoestrogens, with a particular focus on isoflavones, has emerged as they can bind to estrogen receptors and may mimic the roles of endogenous estrogen. Fermented red clover extract (RC) contains isoflavones with superior bioavailability compared to non-fermented isoflavones, however little is known regarding the impact of isoflavones on cardiovascular and metabolic health. We assessed markers of vascular health in plasma and skeletal muscle samples obtained from healthy but sedentary early post-menopausal women (

Indexed as

cardiovascular healthfermented red cloverisoflavonesphytoestrogenpost-menopausal womenskeletal muscle microcirculationsupplementationvascular inflammation

Identifiers

PMID35224058
PMCPMC8866445
OpenAlexW4211058669

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.