Evidence map›Paper›PMID 35223801›Full record

ArticleFrontiers in bioengineering and biotechnology2022

Biomimetic Cucurbitacin B-Polydopamine Nanoparticles for Synergistic Chemo-Photothermal Therapy of Breast Cancer.

Junke Leng, Xiaofeng Dai, Xiao Cheng, Hao Zhou, Dong Wang, Jing Zhao, Kun Ma, Changhao Cui, Li Wang, Zhaoming Guo

Open access · goldAbstract read
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Profiling and cheminformatics bioprospection of curcurbitacin I and momordin Ic fromJournal of enzyme inhibition and medicinal chemistry · 2025
    Article
  3. Review
  4. CaCOHeliyon · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Junke LengSchool of Life and Pharmaceutical Sciences, Dalian University of Technology, Panjin, China.
Xiaofeng DaiSchool of Life and Pharmaceutical Sciences, Dalian University of Technology, Panjin, China.
Xiao ChengSchool of Life and Pharmaceutical Sciences, Dalian University of Technology, Panjin, China.
Hao ZhouSchool of Food and Environment, Dalian University of Technology, Panjin, China.
Dong WangPanjin People's Hospital, Panjin, China.
Jing ZhaoSchool of Life and Pharmaceutical Sciences, Dalian University of Technology, Panjin, China.
Kun MaSchool of Life and Pharmaceutical Sciences, Dalian University of Technology, Panjin, China.
Changhao CuiSchool of Life and Pharmaceutical Sciences, Dalian University of Technology, Panjin, China.
Li WangSchool of Life and Pharmaceutical Sciences, Dalian University of Technology, Panjin, China.
Zhaoming GuoSchool of Life and Pharmaceutical Sciences, Dalian University of Technology, Panjin, China.
Dalian University of Technology · CNDalian University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Breast cancer is the most common malignant tumor in women. Researchers have found that the combined use of multiple methods to treat tumors is a promising strategy. Here, we have developed a biomimetic nano-platform PDA@MB for tumor targeted photothermal therapy (PTT) combined with chemotherapy. The 4T1 cell membrane loaded with cucurbitacin B (CuB) was used to coat polydopamine (PDA) nanoparticles, which gave PDA@MB nanoparticles the ability to target tumors and escape immune cells from phagocytosis. PDA@MB showed excellent photothermal performance including high photothermal conversion efficiency and photostability, and exhibited outstanding

Indexed as

biomimeticcucurbitacin Bphotothermal therapysynergistic treatmenttargeted drug delivery

Identifiers

PMID35223801
PMCPMC8864241
OpenAlexW4210918924

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.