ArticleFrontiers in public health2022
Association Between Functional Limitations and Incident Cardiovascular Diseases and All-Cause Mortality Among the Middle-Aged and Older Adults in China: A Population-Based Prospective Cohort Study.
Article in Frontiers in public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.
- The impact of depression on mortality among older adult patients with hypertension: a systematic review and meta-analysis.Frontiers in public health · 2025Pooled it
- Health-Related Digital Engagement and Incident Stroke Among Older Adults: Prospective Cohort Study.Journal of medical Internet research · 2026Article
- Functional limitation and cardiometabolic health: a cross-sectional exploration in adults aged 30 and older in rural Punjab, India.BMC public health · 2026Article
- Long-term trajectories of memory, depression, and mobility independence before death: a multi-cohort study.Translational psychiatry · 2026Article
- Examining the Association Between Occupational Strain and Risk of Angina Pectoris Among Older Working Adults in India Using Karasek's Job Demand Control Model.Research square · 2026Article
- Exploring the Joint Impact of METS-VF and Functional Limitation on Cardiometabolic Multimorbidity Risk.Journal of diabetes research · 2026Article
- Relationship between sarcopenia and cardiovascular disease among middle-aged and older adults with normal weight in China: functional limitation plays a mediating role.Environmental health and preventive medicine · 2025Article
- Article
- Patient-reported predictors of postdischarge mortality after cardiac hospitalization.Journal of hospital medicine · 2024Article
- Association of handgrip strength asymmetry and weakness with functional disability among middle-aged and older adults in China.Journal of global health · 2024Article
- Hypertension combined with limitations in activities of daily living and the risk for cardiovascular disease.BMC geriatrics · 2024Article
- The bidirectional relationship between activities of daily living and frailty during short-and long-term follow-up period among the middle-aged and older population: findings from the Chinese nationwide cohort study.Frontiers in public health · 2024Article
- Association between depression and endometriosis using data from NHANES 2005-2006.Scientific reports · 2023Article
- Does the integration of urban and rural health insurance influence the functional limitations of the middle-aged and elderly in rural China?SSM - population health · 2023Article
- Long-Term Influence of Locus of Control and Quality of Life on Metabolic Profile in Elderly Subjects with Type 2 Diabetes.International journal of environmental research and public health · 2022Article
- Sex Differences in Frequency of Instrumental Activities of Daily Living after Cardiac Rehabilitation and Its Impact on Outcomes in Patients with Heart Failure.Journal of cardiovascular development and disease · 2022Article
- Effects of functional limitations and activities of daily living on the mortality of the older people: A cohort study in China.Frontiers in public health · 2022Article
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Authors and funding
5 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe prevalence of functional limitations is relatively high among the middle-aged and older adults. However, the contribution of functional limitations to subsequent incident cardiovascular diseases (CVD) and death is unclear. This study aims to examine the association between functional limitations and incident CVD and all-cause mortality among the middle-aged and older adults.
methodsThis is a nationally representative prospective cohort study. Participants were middle-aged and older Chinese adults from The China Health and Retirement Longitudinal Study. Functional limitations were measured using activities of daily living (ADL) scale and instrumental activities of daily living (IADL) scale. Incident CVD and death were recorded at followed-up from June 1, 2011, up until August 31, 2018. Cox proportional hazards model was used to assess the association between functional limitations and incident CVD and all-cause mortality.
resultsA total of 11,013 participants were included in this study. During the 7 years of follow-up, 1,914 incident CVD and 1,182 incident deaths were identified. Participants with functional limitations were associated with a 23% increased risk of incident CVD (HR, 1.23, 95% CI:1.08,1.39) after adjusting for age, gender, residential area, marital status, education, smoking, alcohol drinking, sleep duration, nap duration, depression symptoms, social participation, history of hypertension, diabetes, dyslipidemia, use of hypertension medications, diabetes medications, and lipid-lowering therapy. Moreover, participants with functional limitations were associated with a 63% increased risk of all-cause mortality (HR,1.63, 95%CI: 1.41,1.89) after adjusting for potential confounders.
conclusionsFunctional limitations were significantly associated with subsequent incident CVD and death among the middle-aged and older Chinese adults.
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