Evidence map›Paper›PMID 35223382›Full record

ArticleNanotheranostics2022

Lanthanide-based β-Tricalcium Phosphate Upconversion Nanoparticles as an Effective Theranostic Nonviral Vectors for Image-Guided Gene Therapy.

Flavia Rodrigues Oliveira Silva, Nelson Batista Lima, Maria Helena Bellini, Luiz Felipe Silva Teixeira, Eric Yiwei Du, Niloufar Jamshidi, Justin Gooding, Adam David Martin, Alexander Macmillan, Christopher Peter Marquis and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nanotheranostics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Flavia Rodrigues Oliveira SilvaInstituto de Pesquisas Energéticas e Nucleares, São Paulo, 05508-000, Brazil.
Nelson Batista LimaInstituto de Pesquisas Energéticas e Nucleares, São Paulo, 05508-000, Brazil.
Maria Helena BelliniInstituto de Pesquisas Energéticas e Nucleares, São Paulo, 05508-000, Brazil.
Luiz Felipe Silva TeixeiraInstituto de Pesquisas Energéticas e Nucleares, São Paulo, 05508-000, Brazil.
Eric Yiwei DuSchool of Chemistry, Faculty of Science, The University of New South Wales, Sydney NSW 2052, Australia.
Niloufar JamshidiSchool of Chemistry, Faculty of Science, The University of New South Wales, Sydney NSW 2052, Australia.
Justin GoodingSchool of Chemistry, Faculty of Science, The University of New South Wales, Sydney NSW 2052, Australia.
Adam David MartinDementia Research Centre, Department of Biomedical Sciences, Macquarie University, Sydney, NSW 2019, Australia.
Alexander MacmillanKatharina Gaus Light Microscopy Facility, Mark Wainwright Analytical Centre, Lowy Cancer Research Centre, The University of New South Wales, Sydney, NSW 2052, Australia.
Christopher Peter MarquisSchool of Biotechnology and Biomolecular Sciences, Faculty of Science, The University of New South Wales, Sydney NSW 2052, Australia.
Pall ThordarsonSchool of Chemistry, Faculty of Science, The University of New South Wales, Sydney NSW 2052, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lanthanide-based beta-tricalcium phosphate (β-TCP) upconversion nanoparticles are exploited as a non-viral vector for imaging guided-gene therapy by virtue of their unique optical properties and multi-modality imaging ability, high transfection efficiency, high biocompatibility, dispersibility, simplicity of synthesis and surface modification. Ytterbium and thulium-doped β-TCP nanoparticles (βTCPYbTm) are synthesized via co-precipitation method, coated with polyethylenimine (PEI) and functionalized with a nuclear-targeting peptide (TAT). Further,

Indexed as

Lanthanoid Series ElementsNanoparticlesCalcium PhosphatesGenetic TherapyHeLa CellsHumansPrecision Medicinebeta-tricalcium phosphateCalcium PhosphatesLanthanoid Series Elementsgene therapy.lanthanide-based β-TCPNIR upconversion theranostic nanoparticlesPEITAT

Identifiers

PMID35223382
PMCPMC8864251

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.