Evidence map›Paper›PMID 35223261›Full record

ArticleCureus2022

A Late Diagnosis of Transthyretin Amyloidosis.

Kristopher S Pfirman, William Newton, Collins Garst, Sharvil Patel, Jacqueline Dawson Dowe

Open access · diamondAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Cureus, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 60% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Kristopher S PfirmanCardiology, Geisinger Medical Center, Danville, USA.
William NewtonMedical Student, University of Kentucky College of Medicine, Bowling Green, USA.
Collins GarstInternal Medicine, Camden Clark, Parkersburg, USA.
Sharvil PatelMedical Student, Edward Via College of Osteopathic Medicine, Spartanburg, USA.
Jacqueline Dawson DoweCardiology, Western Kentucky Heart, Lung, and Gastroenterology, Bowling Green, USA.
Geisinger Medical Center · USArk Medical Center · USBowling Green State University · USEdward Via College of Osteopathic Medicine · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiac amyloidosis is a rare disease caused by the accumulation of protein-based fibrils that deposit into the myocardium, causing disease. The accumulation of amyloid in the heart tissue causes the heart to become increasingly stiff, reducing compliance, with the eventual decline of the heart's systolic function over time as the disease progresses. The restrictive physiology of the disease usually prompts investigation; however, if allowed to progress, the systolic function becomes affected in the later stages of the disease. We present a case of late-stage transthyretin-related amyloidosis (ATTR).

Indexed as

diastolic heart failureechocardiographyend stage renal disease (esrd)pyptransthyretin amyloidosis

Identifiers

PMID35223261
PMCPMC8858644
OpenAlexW4207029825

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.