ArticleDermatology practical & conceptual2022
Collagen Supplements for Aging and Wrinkles: A Paradigm Shift in the Fields of Dermatology and Cosmetics.
Article in Dermatology practical & conceptual, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
48 citing papers in PubMed, 2 syntheses or guidelines pooled it, 79 citations in OpenAlex.
- Hydrogen Water: Extra Healthy or a Hoax?-A Systematic Review.International journal of molecular sciences · 2024Pooled it
- Potential Utilisation of Secretome from Ascorbic Acid-Supplemented Stem Cells in Combating Skin Aging: Systematic Review of A Novel Idea.Cell journal · 2023Pooled it
- Effectiveness and Safety of Recombinant Type III Humanized Collagen Solution Injection Combined With Collagen-III Multi-Peptide Serum in Improving Signs of Photoaging: A Prospective, Split-Face Controlled Clinical Trial.Journal of cosmetic dermatology · 2026Trial
- Anti-Wrinkle and Skin Moisture Efficacy of 7-MEGANutrients · 2024Trial
- Collagen, Curcumin, and Glutathione to Enhance Dermal Health in Aging Women with Declining Estrogen Levels -A Narrative Review.Dermatology and therapy · 2026Review
- Analysis of total and free amino acid compositions of fishery byproducts from three commonly consumed fish species in South Korea.Amino acids · 2026Article
- Novel Palmitoyl Pentapeptides: Self-Assembly, Collagen Stimulation, Antioxidant Activity, and Influence of Skin Microbiota Health.ACS omega · 2026Article
- Sea Cucumber Collagen Peptides Exert an Anti-Skin Aging Effect by Inhibiting Endoplasmic Reticulum Stress in Fibroblasts.Foods (Basel, Switzerland) · 2026Article
- Antarctic soil microbiomes as a reservoir for cosmetic bioactives: continental-scale diversity and predicted functions.Genes & genomics · 2026Article
- Evaluation of the safety and functional effects of recombinant humanized type III collagen in food toxicology.Frontiers in medicine · 2026Article
- Efficacy of an Oral Skincare Supplement on Skin Aging: A 12-Week Randomized, Double-Blind, Placebo-Controlled Trial.Dermatology and therapy · 2025Article
- Benefits and risks of hair, skin, and nail supplements in older adults.International journal of women's dermatology · 2025Review
- Deciphering the molecular clock: exploring molecular mechanisms and genetic influences on skin ageing.Biogerontology · 2025Review
- Article
- A Comprehensive Review on the Valorization of Bioactives from Marine Animal By-Products for Health-Promoting, Biofunctional Cosmetics.Marine drugs · 2025Review
- Recombinant Type III Humanized Collagen Solution for Injection Improves Skin Photoaging in Chinese Population: A Case Series.Journal of cosmetic dermatology · 2025Article
- Food-Derived Micronutrients as Alleviators of Age-Related Dysfunction: A Dive into Their Effects and Cellular Mechanisms.Indian journal of clinical biochemistry : IJCB · 2025Review
- Article
- Unveiling the Role of Sweet Potato Root in Skin Health: A New Approach to Collagen Synthesis and Rejuvenation.Food science & nutrition · 2025Review
- Natural Compounds with Beneficial Effects on Skin Collagen Type I and Mechanisms of Their Action.Antioxidants (Basel, Switzerland) · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionSlowing the aging process by use of collagen supplements has become a driving force in the field of dermatology and cosmetics. Generally, oral and topical collagen are used in anti-aging products, as reported in the literature.
objectivesThe overarching goal of this research is to collate the consequences of oral collagen with those of topical collagen in reducing or delaying the aging process.
methodsWe executed an electronic search in Google Scholar and PubMed. We considered a study eligible if it was original research, published in English between 2010 and 2020, and if it provided information on the topic of collagen and aging. We retrieved 12 full-text articles, and these were assessed by reviewers independently.
resultsAll human studies included in the review were randomized controlled trials mainly conducted in high- to middle-income countries which highlighted that both oral and topical collagen supplements help to delay the aging process, with no differences arising between the two types of collagen. The evidence from the reviewed studies suggested that both collagen supplements improve skin moisture, elasticity, and hydration when orally administered. Additionally, collagen reduces the wrinkling and roughness of the skin, and existing studies have not found any side effects of its oral supplements.
conclusionsBoth oral and topical collagen can contribute to reducing or delaying skin aging. Future epidemiological studies with large sample sizes and thorough follow-up measures would be required to comprehensively understand the potential effects of these two types of collagen on the aging process.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.