Evidence map›Paper›PMID 35223098›Full record

ArticleInternational journal of nephrology2022

Intravenous Administration of Cisplatin with Magnesium Sulfate Supplement May Prevent Kidney Toxicity in Rats: The Role of Gender and Magnesium Sulfate Dose.

Parisa Pournaderi, Behnaz Pourvali, Farzaneh Ashrafi, Ardeshir Talebi, Zahra Pezeshki, Mehdi Nematbakhsh

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of nephrology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 56% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Parisa PournaderiWater & Electrolytes Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
Behnaz PourvaliWater & Electrolytes Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
Farzaneh AshrafiWater & Electrolytes Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
Ardeshir TalebiWater & Electrolytes Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
Zahra PezeshkiWater & Electrolytes Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
Mehdi NematbakhshWater & Electrolytes Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.ORCID https://orcid.org/0000-0002-9565-9187
Isfahan University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCisplatin (CP) is widely used to treat various kinds of malignancies, but to avoid its side effects of nephrotoxicity and hypomagnesemia, magnesium supplementation is a subject of debate. The current study was designed to determine the protective role of intravenous magnesium sulfate (MgSO

methodIn this case-control experimental study, 80 Wistar male and female rats in 12 groups of experiments were subjected to receive intravenous administration of CP accompanied with intravenous infusion of different doses (1, 3, and 10 mg/ml solution) of MgSO

resultsCP administration increased blood urea nitrogen (BUN), creatinine (Cr), kidney tissue damage score (KTDS), and kidney weight (KW), and they were attenuated by the mid-dose of MgSO

conclusionThe renal protective effect of MgSO

Identifiers

PMID35223098
PMCPMC8866029
OpenAlexW4213125343

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.