Evidence map›Paper›PMID 35222861›Full record

ArticleIranian journal of microbiology2021

Isolation and immunogenicity of extracted outer membrane vesicles from

Mehdi Hadadi-Fishani, Shahin Najar-Peerayeh, Seyed Davar Siadat, Mohammad Sekhavati, Ashraf Mohabati Mobarez

Open access · diamondAbstract read
In one paragraph

Article in Iranian journal of microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Antibiotics Impact the Cytotoxicity and Cytopathic Effect ofInternational journal of molecular sciences · 2025
    Article
  3. Article
  4. Review
  5. Review
  6. American journal of physiology. Lung cellular and molecular physiology · 2024
    Article
  7. Article
  8. Article
  9. Modulation ofBiomedicines · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Mehdi Hadadi-FishaniDepartment of Bacteriology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran.
Shahin Najar-PeerayehDepartment of Bacteriology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran.
Seyed Davar SiadatDepartment of Mycobacteriology and Pulmonary Research, Pasteur Institute, Tehran, Iran.
Mohammad SekhavatiDepartment of Aerobic Bacterial Research and Vaccine Production, Razi Vaccine and Serum Research Institute, Agricultural Research, Education and Extension Organization (AREEO), Karaj, Iran.
Ashraf Mohabati MobarezDepartment of Bacteriology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran.
Tarbiat Modares University · IRPasteur Institute of Iran · IRRazi Vaccine and Serum Research Institute · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectivesDifferent types of antibiotics have been indicated to enhance the secretion of OMVs from MATERIALS AND

methodsThe OMVs were prepared from

resultsSpecific-antibody IgG production, particularly IgG1 subclass, increased in mice primed with hypervesiculation-derived OMVs compared to normal condition-derived OMVs. Serum bactericidal activity and opsonophagocytosis of secreted antibody was enhanced in mice primed with hypervesiculation-derived OMVs. Investigation of cytokine production showed the upregulation of IL-8, IL-12, IL-17, and TNF-α and downregulation of IL-10.

conclusionBased on our findings, OMVs production can be increased by treating

Indexed as

HypervesiculationImmunizationOuter membrane vesiclePseudomonas aeruginosa

Identifiers

PMID35222861
PMCPMC8816698
OpenAlexW4200128855

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.