Evidence map›Paper›PMID 35222761›Full record

ArticleJournal of arrhythmia2022

Multimorbidity, polypharmacy, and mortality in older patients with pacemakers.

Toshihiko Goto, Kento Mori, Takafumi Nakayama, Junki Yamamoto, Yasuhiro Shintani, Kazuaki Wakami, Hidekatsu Fukuta, Yoshihiro Seo, Nobuyuki Ohte

Open access · goldAbstract read
In one paragraph

Article in Journal of arrhythmia, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Toshihiko GotoDepartment of Cardiology Nagoya City University Graduate School of Medical Sciences Nagoya Japan.ORCID https://orcid.org/0000-0001-7132-2806
Kento MoriDepartment of Cardiology Nagoya City University Graduate School of Medical Sciences Nagoya Japan.
Takafumi NakayamaDepartment of Cardiology Nagoya City University Graduate School of Medical Sciences Nagoya Japan.
Junki YamamotoDepartment of Cardiology Nagoya City University Graduate School of Medical Sciences Nagoya Japan.
Yasuhiro ShintaniDepartment of Cardiology Nagoya City University Graduate School of Medical Sciences Nagoya Japan.
Kazuaki WakamiDepartment of Cardiology Nagoya City University Graduate School of Medical Sciences Nagoya Japan.
Hidekatsu FukutaClinical Research Management Center Nagoya City University Hospital Nagoya Japan.
Yoshihiro SeoDepartment of Cardiology Nagoya City University Graduate School of Medical Sciences Nagoya Japan.
Nobuyuki OhteDepartment of Cardiovascular Medicine Nagoya City University East Medical Center Nagoya Japan.
Nagoya City University · JPNagoya City University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe prevalence of multimorbidity and polypharmacy and its association with all-cause mortality in older patients with pacemakers are largely unknown. We aimed to clarify the prevalence of multimorbidity and polypharmacy, and its association with all-cause mortality in patients ≥75 years of age with pacemakers.

methodsWe retrospectively investigated 256 patients aged ≥75 years (mean age 84.0 ± 5.3 years; 45.7% male) with newly implanted pacemakers. The study endpoint was all-cause mortality ("with events"). Multimorbidity was defined as a Charlson Comorbidity Index ≥3. Polypharmacy was defined as the use of ≥5 medications.

resultsDuring the follow-up period (median, 3.1 years), 60 all-cause deaths were reported. The Charlson Comorbidity Index (2.9 ± 1.9 vs. 1.7 ± 1.7,

conclusionsMultimorbidity and its associated polypharmacy, which are common in the older population, are prevalent in patients with pacemakers and are independent predictors of poor prognosis.

Indexed as

mortalitymultimorbidityolder patientspacemakerspolypharmacy

Identifiers

PMID35222761
PMCPMC8851581
OpenAlexW3216700033

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.