ArticleMindfulness2022
Differential Brain Perfusion Changes Following Two Mind-Body Interventions for Fibromyalgia Patients: an Arterial Spin Labelling fMRI Study.
Article in Mindfulness, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02561416 (Cost-utility and Biological Underpinnings of Mindfulness-Based Stress Reduction), which is not on this map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Cost-utility and Biological Underpinnings of Mindfulness-Based Stress Reduction (MBSR) in Fibromyalgia Syndrome: A Three-arm Randomized, Controlled Trial (EUDAIMON Project)
Who cites it
4 citing papers in PubMed, 8 citations in OpenAlex.
- Does practice make perfect? Functional connectivity of the salience network and somatosensory network predicts response to mind-body treatments for fibromyalgia.Frontiers in pain research (Lausanne, Switzerland) · 2024Article
- Mind-body practices, interoception and pain: a scoping review of behavioral and neural correlates.Annals of medicine · 2023Article
- Research in Mindfulness Interventions for Patients With Fibromyalgia: A Critical Review.Frontiers in integrative neuroscience · 2022Review
- Entrepreneurial mindfulness and organizational resilience of Chinese SMEs during the COVID-19 pandemic: The role of entrepreneurial resilience.Frontiers in psychology · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesFurther mechanistic insight on mind-body techniques for fibromyalgia (FMS) is needed. Arterial spin labelling (ASL) imaging can capture changes in regional cerebral blood flow (rCBF) that relate to spontaneous pain.
methodsWe recruited FMS patients undergoing either mindfulness-based stress reduction training (MBSR,
resultsWe identified a significant interaction effect in the amygdala, which corresponded with rCBF decreases following FibroQoL specifically. At baseline, rCBF in the amygdala for the FibroQoL group correlated with pain catastrophizing and anxiety scores, but not after treatment, suggesting a decoupling between activity in the amygdala and negative emotional symptoms of FMS as a consequence of treatment. Baseline rCBF correlated positively with pain symptoms in the ACC and the anterior insula across all patients; moreover, the correlation between rCBF changes post intervention in the insula and pain improvement was negative for both treatments and significantly different from the control group. We suggest that there is disruption of the typical relationship between clinical pain and activity as a product of these two nonpharmacological therapies.
conclusionsWe have demonstrated that different mind-to-body treatments correspond to differential changes in clinical symptoms and brain activity patterns, which encourages future research investigating predictors of treatment response.
trial registrationNCT02561416. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s12671-021-01806-2.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.