Evidence map›Paper›PMID 35222675›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2022

Tetrandrine Ameliorates Rheumatoid Arthritis in Mice by Alleviating Neutrophil Activities.

Qingyi Lu, Haixu Jiang, Qingqing Zhu, Jie Xu, Yanan Cai, Guiyang Huo, Kai Yuan, Guangrui Huang, Anlong Xu

Open access · hybridAbstract read
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

  1. Efficacy and safety of tetrandrine in treatment of rheumatoid arthritis: a meta-analysis.Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2024
    Pooled it
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  6. NETs: a new target for autoimmune disease.Frontiers in immunology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Qingyi LuSchool of Life Sciences, Beijing University of Chinese Medicine, Beijing, China.ORCID https://orcid.org/0000-0003-0738-8725
Haixu JiangSchool of Life Sciences, Beijing University of Chinese Medicine, Beijing, China.ORCID https://orcid.org/0000-0002-4510-7042
Qingqing ZhuSchool of Life Sciences, Beijing University of Chinese Medicine, Beijing, China.ORCID https://orcid.org/0000-0001-5344-7648
Jie XuSchool of Life Sciences, Beijing University of Chinese Medicine, Beijing, China.ORCID https://orcid.org/0000-0003-2925-6547
Yanan CaiSchool of Life Sciences, Beijing University of Chinese Medicine, Beijing, China.ORCID https://orcid.org/0000-0002-1131-4959
Guiyang HuoSchool of Life Sciences, Beijing University of Chinese Medicine, Beijing, China.ORCID https://orcid.org/0000-0002-0679-5284
Kai YuanSchool of Life Sciences, Beijing University of Chinese Medicine, Beijing, China.ORCID https://orcid.org/0000-0001-7239-449X
Guangrui HuangSchool of Life Sciences, Beijing University of Chinese Medicine, Beijing, China.ORCID https://orcid.org/0000-0003-1846-0227
Anlong XuSchool of Life Sciences, Beijing University of Chinese Medicine, Beijing, China.ORCID https://orcid.org/0000-0002-2948-3507
Beijing University of Chinese Medicine · CNSun Yat-sen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rheumatoid arthritis (RA) is a common autoimmune disease worldwide. Neutrophils play critical roles in the onset and development of RA and are the promising target for RA treatment. Tetrandrine is a bis-benzyl isoquinoline alkaloid derived from the traditional Chinese herbal

Identifiers

PMID35222675
PMCPMC8865980
OpenAlexW4213273226

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.