Evidence map›Paper›PMID 35222618›Full record

ArticleJournal of data science : JDS2021

Sign-based Shrinkage Based on an Asymmetric LASSO Penalty.

Eric S Kawaguchi, Burcu F Darst, Kan Wang, David V Conti

Open access · diamondAbstract read
In one paragraph

Article in Journal of data science : JDS, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Eric S KawaguchiDepartment of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.
Burcu F DarstDepartment of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.
Kan WangGoogle, Mountain View, California, USA.
David V ContiDepartment of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.
University of Southern California · USGoogle (United States) · US

Funding

USC/NORRIS COMPREHENSIVE CANCER CENTER (CORE) SUPPORTP30CA014089 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Fumito Ito · 1985 to 2026
$181.4M
Statistical Methods for Integrative Genomics in CancerP01CA196569 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI William JAMES GAUDERMAN, KIMBERLY D SIEGMUND · 2016 to 2026
$25.5M
PAGE III: Population Architecture using Genomics and EpidemiologyR01HG010297 · NHGRI · RUTGERS, THE STATE UNIV OF N.J. · PI GIGNOUX, CHRISTOPHER R, MATISE, TARA C. · 2019 to 2022
$6.5M
Training Grant in Genomic Analysis and InterpretationT32ES013678 · NIEHS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI GAUDERMAN, WILLIAM JAMES, MCCONNELL, ROB S · 2006 to 2023
$5.6M
Leveraging Prospective Cancer Epidemiology Cohorts and Novel Methods to Improve Polygenic Risk ScoresU01CA261339 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Fei Chen, David V Conti · 2021 to 2026
$5.2M
Precision Prostate Cancer Screening with Genetically Adjusted Prostate-Specific Antigen LevelsR01CA241410 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI John S. Witte · 2020 to 2026
$3.7M
Multiethnic GWAS and TWAS to Inform Risk Prediction for Prostate CancerU01CA257328 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI CONTI, DAVID V, HAIMAN, CHRISTOPHER ALAN · 2021 to 2025
$3.1M
Integrating Genomics and Metabolomics to Develop Predictive Models of Prostate Cancer in Multiethnic MenK99CA246063 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI DARST, BURCU FRANCES · 2020 to 2021
$246k
NCI NIH HHS K99 CA246063NCI NIH HHS P01 CA196569NCI NIH HHS P30 CA014089NCI NIH HHS R01 CA241410NCI NIH HHS U01 CA257328NCI NIH HHS U01 CA261339NHGRI NIH HHS R01 HG010297NIEHS NIH HHS T32 ES013678
6 · The paper itself

Abstract

Penalized regression provides an automated approach to preform simultaneous variable selection and parameter estimation and is a popular method to analyze high-dimensional data. Since the conception of the LASSO in the mid-to-late 1990s, extensive research has been done to improve penalized regression. The LASSO, and several of its variations, performs penalization symmetrically around zero. Thus, variables with the same magnitude are shrunk the same regardless of the direction of effect. To the best of our knowledge, sign-based shrinkage, preferential shrinkage based on the sign of the coefficients, has yet to be explored under the LASSO framework. We propose a generalization to the LASSO, asymmetric LASSO, that performs sign-based shrinkage. Our method is motivated by placing an asymmetric Laplace prior on the regression coefficients, rather than a symmetric Laplace prior. This corresponds to an asymmetric

Indexed as

asymmetric Laplace distributionhigh-dimensional statisticspenalized regressionquantile regularizationvariable selection

Identifiers

PMID35222618
PMCPMC8880910
OpenAlexW3166547076

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.