Evidence map›Paper›PMID 35222566›Full record

ArticleAfrican health sciences2021

Adherence to oral HIV pre-exposure prophylaxis among female sex workers in Kampala, Uganda.

Grace Kakoola Nalukwago, John Bosco Isunju, Timothy Muwonge, Thomas Katairo, Nelson Bunani, Fred Semitala, Peter Kyambadde, Flavia Matovu

Open access · diamondAbstract read
In one paragraph

Article in African health sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 15 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Grace Kakoola NalukwagoMakerere University College of Health Sciences, Public Health.
John Bosco IsunjuMakerere University College of Health Sciences, Public Health.
Timothy MuwongeMakerere University Infectious Diseases Institute, Research.
Thomas KatairoMakerere University College of Health Sciences, School of Medicine, Clinical Epidemiology Unit.
Nelson BunaniMakerere University College of Health Sciences, Public Health.
Fred SemitalaMakerere University College of Health Sciences, School of Medicine, Clinical Epidemiology Unit.
Peter KyambaddeMost at Risk Population Iniatives (MarPI).
Flavia MatovuMakerere University School of Public Health, Epidemiology and Biostatistics.
Makerere University · UGMUJHU Research Collaboration · UGPopulation Council · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionIn Kampala Uganda, female sex workers (FSWs) have high HIV prevalence (33%). Oral PrEP is a novel HIV prevention intervention that offers hope to decrease HIV incidence in key populations especially among FSWs. Studies have shown that with poor adherence, oral PrEP has no efficacy, and therefore adherence to PrEP is critical among FSWs to maximize HIV prevention. However, implementation data on adherence to PrEP among FSWs is limited so this study sought to assess adherence to PrEP. Specifically, we sought to 1) determine the level of adherence to PrEP among FSWs, and 2) determine factors associated with PrEP adherence.

methodsThis cross-sectional study was conducted from November to December 2018; 126 FSWs using PrEP were interviewed using a questionnaire. Adherence was categorically defined as high adherence and low adherence. Logistic regression was done.

resultsUsing long-term contraception methods (OR 0.06, 95% CI: 0.04-0.77) and not using condoms with clients (OR 0.07, 95% CI: 0.01-0.42) were negatively associated with high PrEP adherence.

conclusionBarriers to PrEP adherence need to be addressed for successful PrEP implementation to improve adherence going forward. Service care providers should reinforce positive behaviors such as use of condoms devotedly during PrEP breaks.

Indexed as

Anti-HIV AgentsHIV InfectionsPre-Exposure ProphylaxisSex WorkersCross-Sectional StudiesFemaleHumansUgandaAnti-HIV Agentsadherencefemale sex workersOral PrEP

Identifiers

PMID35222566
PMCPMC8843287
OpenAlexW3203928006

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.