Evidence map›Paper›PMID 35222560›Full record

ArticleAfrican health sciences2021

Predictors for tuberculosis co-infection in people living with HIV/AIDs.

Esra Zerdali, İnci Yılmaz Nakir, Serkan Sürme, Uğurcan Sayılı, Mustafa Yıldırım

Open access · diamondAbstract read
In one paragraph

Article in African health sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.9field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Tuberculosis among Ambulatory People Living with HIV in Guangxi Province, China: A Longitudinal Study.International journal of environmental research and public health · 2022
    Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 3 countries.

Esra ZerdaliHaseki Education Research Hospital, Infectious Diseases and Clinical Microbiology, İstanbul, Turkey.
İnci Yılmaz NakirHaseki Education Research Hospital, Infectious Diseases and Clinical Microbiology, İstanbul, Turkey.
Serkan SürmeHaseki Education Research Hospital, Infectious Diseases and Clinical Microbiology, İstanbul, Turkey.
Uğurcan SayılıKaraköprü District Health Directorate, Public Health, Şanlıurfa, Turkey.
Mustafa YıldırımHaseki Education Research Hospital, Infectious Diseases and Clinical Microbiology, İstanbul, Turkey.
Directorate of Health · ISEducation and Research Institute · USHaseki Eğitim ve Araştırma Hastanesi · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimTuberculosis (TB) is one of the most common chronic infectious conditions causing mortality and severe outcomes, particularly in people living with HIV/AIDS (PLWHA). In this study, we aimed to determine the prevalence and predictors of TB among PLWHA. MATERIALS AND

methodsWe conducted a retrospective and single-center study of adults (≥18 years) PLWHA registered at our tertiary teaching and research hospital between 2000 and 2016.

resultsA total of 711 PLWHA were included. Of whom, 633 (89.0%) were male. Mean age was 36.53 ±11.55 years (range, 17-79). Thirty-eight (5.3%) patients were diagnosed with active TB. TB development was associated with low CD4+ lymphocyte count (p<0.001), high viral load (p=0.040) and alcohol consumption (p=0.004) but no association with age (p=0.392), gender (p=0.928) and duration since anti-retroviral therapy initiation (p=0.788) was found. Also, a receiver operating characteristic analysis showed that the area under the curves of CD4+ lymphocyte count as a predictor for TB development in PLWHA was 0.717 (p<0.001).

conclusionThere are still clinical challenges to predict TB diagnosis. However, CD4+ lymphocyte count and viral load may be considered as valuable predictors for TB development. Also, community strategies to reduce harmful effect of alcohol use should be developed.

Indexed as

Acquired Immunodeficiency SyndromeCoinfectionHIV InfectionsTuberculosisAdultCD4 Lymphocyte CountHumansMaleMiddle AgedRetrospective StudiesYoung AdultCD4 cell countsHIV viral loadTuberculosis

Identifiers

PMID35222560
PMCPMC8843284
OpenAlexW3203537425

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.