Evidence map›Paper›PMID 35222559›Full record

ArticleAfrican health sciences2021

It is not always Tuberculosis! A case of pulmonary cryptococcosis in an immunocompetent child in Uganda.

Irene Nakatudde, Phillip Kasirye, Sarah Kiguli, Philippa Musoke

Open access · diamondAbstract readCase Reports
In one paragraph

Article in African health sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Irene NakatuddeDepartment of Paediatrics and Child Health, College of Health Sciences, Makerere University.
Phillip KasiryeMulago National Referral Hospital, Kampala, Uganda.
Sarah KiguliDepartment of Paediatrics and Child Health, College of Health Sciences, Makerere University.
Philippa MusokeDepartment of Paediatrics and Child Health, College of Health Sciences, Makerere University.
Makerere University · UGMUJHU Research Collaboration · UGMulago Hospital · UG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pulmonary cryptococcosis is rare in immunocompetent individuals. Limited data exist regarding its occurrence in children, especially in developing countries. This case report describes an 8-year-old HIV-negative child with pulmonary cryptococcosis, previously diagnosed and treated for tuberculosis twice without improvement. Fine needle aspiration biopsy confirmed the diagnosis of pulmonary cryptococcosis and serum cryptococcal antigen test was positive. The child improved on amphotericin and fluconazole treatment. Despite the limited diagnostic capacity in many resource-constrained settings like Uganda, this case report highlights the need to investigate other causes of pneumonia in immunocompetent children that are not improving on conventional antimicrobial treatments.

Indexed as

CryptococcosisTuberculosisAntifungal AgentsChildFluconazoleHumansUgandaAntifungal AgentsFluconazolechildrenimmunocompetentPulmonary cryptococcosisUganda

Identifiers

PMID35222559
PMCPMC8843282
OpenAlexW3203803513

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.