Evidence map›Paper›PMID 35222557›Full record

ArticleAfrican health sciences2021

Comparative yield of different active TB case finding interventions in a large urban TB project in central Uganda: a descriptive study.

Andrew Kazibwe, Fred Twinomugisha, Joseph Musaazi, Florence Nakaggwa, Disan Lukanga, Phillip Aleu, Timothy Kiyemba, Abel Nkolo, Nicholas Sebuliba Kirirabwa, Debora B Freitas Lopez and 3 more

Abstract read
In one paragraph

Article in African health sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Andrew KazibweThe AIDS Support Organization, Kampala, Uganda.
Fred TwinomugishaUSAID/Defeat TB Project, University Research Co. LLC, Kampala, Uganda.
Joseph MusaaziThe Infectious Diseases Institute, College of Health Sciences, Makerere University, Kampala, Uganda.
Florence NakaggwaUSAID/Defeat TB Project, University Research Co. LLC, Kampala, Uganda.
Disan LukangaThe AIDS Support Organization, Kampala, Uganda.
Phillip AleuUSAID/Defeat TB Project, University Research Co. LLC, Kampala, Uganda.
Timothy KiyembaUSAID/Defeat TB Project, University Research Co. LLC, Kampala, Uganda.
Abel NkoloUSAID/Defeat TB Project, University Research Co. LLC, Kampala, Uganda.
Nicholas Sebuliba KirirabwaUSAID/Defeat TB Project, University Research Co. LLC, Kampala, Uganda.
Debora B Freitas LopezUniversity Research Co. LLC, Maryland, US.
Estella BirabwaUSAID Uganda.
Seyoum DejeneUSAID Uganda.
Stella Zawedde-MuyanjaUSAID/Defeat TB Project, University Research Co. LLC, Kampala, Uganda.

Funding

HIV Co-infections in Uganda: TB, Cryptococcus, and Viral Hepatitis.D43TW009771 · FIC · JOHNS HOPKINS UNIVERSITY · PI CASTELNUOVO, BARBARA, KAMBUGU, ANDREW DDUNGU · 2014 to 2023
$3.3M
FIC NIH HHS D43 TW009771
6 · The paper itself

Abstract

introductionSystematic screening for TB among patients presenting to care and among high risk populations is recommended to improve TB case finding. We aimed to describe the comparative yield of three TB screening approaches implemented by a large urban TB project in central Uganda.

methodsWe abstracted data on the screening cascade from 65 health facilities and their surrounding communities (numbers screened, with presumptive TB, receiving a diagnostic test and diagnosed with TB) from the different clinic and community TB registers.

resultsFrom January 2018 to December 2019, 93,378 (24%) of all patients screened at health facilities had presumptive TB; 77,381 (82.9%) received a diagnostic test and 14,305 (18.5%) were diagnosed with TB. The screening yield (the number of patients diagnosed with TB out of all patients screened) was 0.3% and was three times higher among men than women (0.6% vs 0.2% p<0.01). During targeted community screening interventions, 9874 (21.1%) of all patients screened had presumptive TB; 7034 (71.2%) of these received a diagnostic test and 1699 (24.2%) were diagnosed with TB. The screening yield was higher among men, (3.7% vs 3.3% p<0.01) and highest among children 0-14 (4.8% vs 3.2% p<0.01).

conclusionTargeted community TB screening interventions improve access to TB diagnosis for men and children 0-14 years.

Indexed as

TuberculosisChildDelivery of Health CareFemaleHealth FacilitiesHumansMaleMass ScreeningUgandacommunityscreeningTuberculosisUganda

Identifiers

PMID35222557
PMCPMC8843286

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.