ArticleFrontiers in immunology2022
Thyroid Function and Low Free Triiodothyronine in Chinese Patients With Autoimmune Encephalitis.
Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.
- Contactin-associated protein-like 2 antibody-associated autoimmune encephalitis in children: case reports and systematic review of literature.Acta neurologica Belgica · 2023Pooled it
- Research progress on the association between Hashimoto's thyroiditis and autoimmune encephalitis: a review.Frontiers in immunology · 2026Review
- Clinical implications of free triiodothyronine levels and diagnostic revisions in antibody-negative autoimmune encephalitis.Frontiers in immunology · 2026Article
- Case Report: A case of paraneoplastic autoimmune encephalitis with concurrent anti-GABABR and anti-SOX1 antibody positivity.Frontiers in cellular neuroscience · 2026Article
- Monocyte-to-Albumin Ratio Predicts the Functional Outcome of Adults With Status Epilepticus: An Observational Study.Brain and behavior · 2026Observational
- Role of thyroid function in non-basal ganglia intracerebral hemorrhage prognosis.Journal of endocrinological investigation · 2025Article
- Clinical, thyroid metabolic, and inflammatory features in pediatric patients with post-acute COVID-19 neuropsychiatric symptoms.BMC infectious diseases · 2025Article
- Predictive value of pan-immune-inflammation value in the prognosis of adults with status epilepticus: a retrospective study.Frontiers in aging neuroscience · 2025Article
- Anti-LGI1 encephalitis: clinical presentation, imaging features, and prognostic analysis.Frontiers in neurology · 2025Article
- The value of dynamic changes in FT3 level for predicting 90-day prognosis of HBV-ACLF patients.European journal of medical research · 2024Article
- Thyroid hormones and prognosis in adults with status epilepticus: a retrospective study.Frontiers in endocrinology · 2024Article
- The Hemoglobin, Albumin, Lymphocyte, and Platelet (HALP) Score Predicts the Prognosis of Adults with Status Epilepticus: A Retrospective Study.Journal of inflammation research · 2024Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background and Objectives: Low free triiodothyronine (FT3) is usually associated with worse functional outcome in critical illness; however, the information on thyroid dysfunction and autoimmune encephalitis (AE) is limited. This study aims to evaluate the clinical prognostic value of thyroid function and low-T3 syndrome in patients with multiple subtypes of AE. Methods: In this retrospective study, we identified the hospital records of 319 candidate patients with AE admitted between January 2016 and December 2020. We then extracted the clinical features and outcomes. Modified Rankin scale (mRS) scores were used to evaluate the patients' neurological function. The serum levels of FT3, free thyroxine (FT4), and thyroid-stimulating hormone (TSH) were measured upon admission. Normal thyroid stimulating hormone level with FT3 below the lower limit of the reference interval (2.63 nmol/L) was defined as low-T3 syndrome. Results: A total of 237 AE cases remained after screening. Among these, 57.81% (137/237) were men and the average age at onset was 41 y (interquartile range, 12-61 y). We found that 83.54% (198/237) of the patients had a good prognosis, and 16.46% (39/237) had a poor prognosis. Abnormal thyroid function was observed in 30.80% of these patients, with a relatively greater prevalence in the group with a poor prognosis ( Conclusions: Abnormal thyroid function in AE is frequent, and serum FT3 levels in patients with poor prognosis are significantly lower than in those with good prognosis. Low-T3 syndrome could be a potential candidate for predicting the prognosis of AE following future research.
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