Evidence map›Paper›PMID 35222370›Full record

ArticleFrontiers in immunology2022

MicroRNA-5112 Targets IKKγ to Dampen the Inflammatory Response and Improve Clinical Symptoms in Both Bacterial Infection and DSS-Induced Colitis.

Xilong Kang, Yang Jiao, Yingying Zhou, Chuang Meng, Xiaohui Zhou, Li Song, Xinan Jiao, Zhiming Pan

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.4field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Involvement of icaritin in the regulation of osteocyte exosomal microRNAs.Journal of orthopaedic surgery and research · 2025
    Article
  5. Article
  6. Article
  7. Cells · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Xilong KangJiangsu Key Laboratory of Zoonosis, Yangzhou University, Yangzhou, China.
Yang JiaoJiangsu Key Laboratory of Zoonosis, Yangzhou University, Yangzhou, China.
Yingying ZhouJiangsu Key Laboratory of Zoonosis, Yangzhou University, Yangzhou, China.
Chuang MengJiangsu Key Laboratory of Zoonosis, Yangzhou University, Yangzhou, China.
Xiaohui ZhouPathobiology and Veterinary Science, College of Agriculture, Health and Natural Resources, University of Connecticut, Storrs, CT, United States.
Li SongJiangsu Key Laboratory of Zoonosis, Yangzhou University, Yangzhou, China.
Xinan JiaoJiangsu Key Laboratory of Zoonosis, Yangzhou University, Yangzhou, China.
Zhiming PanJiangsu Key Laboratory of Zoonosis, Yangzhou University, Yangzhou, China.
Yangzhou University · CNUniversity of Connecticut · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inflammation is a double-edged sword that can be induced by various PAMPs, resulting in the control of infection by invading pathogens or injuries. The inflammatory response requires strict and precise control and regulation. MicroRNAs (miRNAs) are small non-coding RNA molecules that regulate gene expression

Indexed as

Bacterial InfectionsColitisMicroRNAsAnimalsCytokinesDextran SulfateFlagellinI-kappa B KinaseInflammationMiceMice, Inbred C57BLCytokinesDextran SulfateFlagellinI-kappa B KinaseMicroRNAsDSS-induced colitisflagellinIKK-γinflammationmiR-5112Salmonella

Identifiers

PMID35222370
PMCPMC8866336
OpenAlexW4211117521

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.