Evidence map›Paper›PMID 35222310›Full record

ArticleFrontiers in microbiology2021

Antiretroviral Imprints and Genomic Plasticity of HIV-1

Jude S Bimela, Aubin J Nanfack, Pengpeng Yang, Shaoxing Dai, Xiang-Peng Kong, Judith N Torimiro, Ralf Duerr

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

Jude S BimelaDepartment of Pathology, New York University School of Medicine, New York, NY, United States.
Aubin J NanfackMedical Diagnostic Center, Yaoundé, Cameroon.
Pengpeng YangYunnan Key Laboratory of Primate Biomedical Research, Institute of Primate Translational Medicine, Kunming University of Science and Technology, Kunming, China.
Shaoxing DaiYunnan Key Laboratory of Primate Biomedical Research, Institute of Primate Translational Medicine, Kunming University of Science and Technology, Kunming, China.
Xiang-Peng KongDepartment of Biochemistry and Molecular Pharmacology, New York University School of Medicine, New York, NY, United States.
Judith N TorimiroChantal Biya International Reference Centre for Research on HIV/AIDS Prevention and Management (CIRCB), Yaoundé, Cameroon.
Ralf DuerrDepartment of Pathology, New York University School of Medicine, New York, NY, United States.
New York University · USCentre International De Reference Chantal Biya · CMKunming University of Science and Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Combinational antiretroviral therapy (cART) is the most effective tool to prevent and control HIV-1 infection without an effective vaccine. However, HIV-1 drug resistance mutations (DRMs) and naturally occurring polymorphisms (NOPs) can abrogate cART efficacy. Here, we aimed to characterize the HIV-1

Indexed as

antiretroviral imprintsCRF02_AGgenomic plasticityHIV-1 polymerase (pol)naturally occurring polymorphisms (NOPs)non-clade B drug resistance mutations (DRMs)reverse transcriptase inhibitors (RTI) versus integrase strand transfer inhibitors (INSTI)treatment intensification in Cameroon

Identifiers

PMID35222310
PMCPMC8864110
OpenAlexW4211251260

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.