Evidence map›Paper›PMID 35222281›Full record

ArticleFrontiers in endocrinology2022

Point of Care Measurement of Body Mass Index and Thyroid Nodule Malignancy Risk Assessment.

Sara Ahmadi, Theodora Pappa, Alex S Kang, Alexandra K Coleman, Iñigo Landa, Ellen Marqusee, Matthew Kim, Trevor E Angell, Erik K Alexander

Open access · goldAbstract read
In one paragraph

Article in Frontiers in endocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
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  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Thyroid Nodules and Obesity.Life (Basel, Switzerland) · 2023
    Review
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Sara AhmadiThyroid Section, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States.
Theodora PappaThyroid Section, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States.
Alex S KangThyroid Section, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States.
Alexandra K ColemanThyroid Section, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States.
Iñigo LandaThyroid Section, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States.
Ellen MarquseeThyroid Section, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States.
Matthew KimThyroid Section, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States.
Trevor E AngellDepartment of Medicine, Division of Endocrinology and Diabetes, Keck School Medicine of USC, Los Angeles, CA, United States.
Erik K AlexanderThyroid Section, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States.
Brigham and Women's Hospital · USHarvard University · USKeck Hospital of USC · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Large scale epidemiology studies have suggested obesity may increase the risk of thyroid cancer, though no prospective analyses using real-world measurement of BMI at a time proximate to initial thyroid nodule evaluation have been performed. Methods: We performed a prospective, cohort analysis over 3 years of consecutive patients presenting for thyroid nodule evaluation. We measured BMI proximate to the time of initial evaluation and correlated this with the final diagnosis of benign or malignant disease. We further correlated patient BMI with aggressivity of thyroid cancer, if detected. Results: Among 1,259 consecutive patients with clinically relevant nodules, 199(15%) were malignant. BMI averaged 28.6 kg/m Conclusion: In contrast to findings published from large scale association studies drawn from national databases, these prospective data of consecutive patients presenting for nodule evaluation detect no association of obesity (as measured by BMI) with thyroid cancer. Real time measurement of BMI at the time of thyroid nodule evaluation does not contribute to cancer risk assessment.

Indexed as

Thyroid NoduleBiopsy, Fine-NeedleBody Mass IndexHumansPoint-of-Care SystemsProspective StudiesRetrospective StudiesRisk AssessmentBMInodule sizeobesitythyroid cancerthyroid nodule

Identifiers

PMID35222281
PMCPMC8873520
OpenAlexW4211195592

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.