ArticleFrontiers in psychology2022
Antipsychotic Polypharmacy and High-Dose Antipsychotic Regimens in the Residential Italian Forensic Psychiatric Population (REMS).
Article in Frontiers in psychology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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14 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Socioenvironmental determinants of polypharmacy in mental health disorders: a systematic review.BMC public health · 2026Pooled it
- Gender differences in sociodemographic, clinical characteristics, and psychopharmacological treatments among forensic ınpatients with serious mental ıllness in Türkiye.International journal of legal medicine · 2026Observational
- [Psychopharmacological treatment of mentally ill offenders : A sample survey of forensic psychiatric patients admitted to two forensic psychiatric facilities in Hesse].Der Nervenarzt · 2026Article
- The prevalence of antipsychotic polypharmacy and its associations with violent behaviors among forensic psychiatry patients.BMC psychiatry · 2026Article
- Prevalence and predictors of high-dose antipsychotic therapy among adult psychiatric inpatients in Baghdad, Iraq.The South African journal of psychiatry : SAJP : the journal of the Society of Psychiatrists of South Africa · 2026Article
- A Thirty-Year Forensic Case Report of Chronic Psychosis: Systemic Implications for Italian Forensic Psychiatry.Healthcare (Basel, Switzerland) · 2025Article
- Pharmacological treatment and psychiatric polypharmacy in forensic psychiatric care in Sweden.European psychiatry : the journal of the Association of European Psychiatrists · 2025Article
- Current status and features of antipsychotic prescriptions in Japanese forensic psychiatric wards based on a forensic inpatient database.Neuropsychopharmacology reports · 2025Article
- Antipsychotic prescribing patterns in a state psychiatric hospital with predominantly forensic admissions.Frontiers in psychiatry · 2025Article
- Antipsychotic prescribing practices and their association with rehospitalization in a forensic psychiatric sample.Frontiers in psychiatry · 2024Article
- Nationwide study on antipsychotic polypharmacy among forensic psychiatric patients.International journal of circumpolar health · 2023Article
- Offenders and non-offenders with schizophrenia spectrum disorders: the crime-preventive potential of sufficient embedment in the mental healthcare and support system.Frontiers in psychiatry · 2023Article
- High Risk, High Dose?-Pharmacotherapeutic Prescription Patterns of Offender and Non-Offender Patients with Schizophrenia Spectrum Disorder.Biomedicines · 2022Article
- Protection of Prisoners with Mental Health Disorders in Italy: Lights and Shadows after the Abolition of Judicial Psychiatric Hospitals.International journal of environmental research and public health · 2022Review
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4 authors.
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Abstract
Few data exist regarding treatment with antipsychotics in forensic psychiatric patient populations with high social dangerousness. We performed a secondary analysis of 681 patients treated with at least one antipsychotic, extracted from a 1-year observational retrospective study, conducted on 730 patients treated in the Italian Residencies for Execution of Security Measures (REMS) (96.4% of the REMS population). We aimed at investigating antipsychotic polypharmacy (prescription of two or more concomitant antipsychotics) and high dose/very high-dose antipsychotics, as well as the possible factors associated with such therapeutic regimens. High dose/very high-dose antipsychotics were defined as a prescribed daily dose to WHO-defined daily dose ratio greater than 1.5 or 3.0, respectively. Binary logistic regression analysis was used in three models to test possible predictors of antipsychotic polypharmacy, high-dose antipsychotics, and very high-dose antipsychotic prescription. Antipsychotic polypharmacy resulted in
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