ArticleFrontiers in physiology2021
Luteinizing Hormone Suppression by Progestin-Primed Ovarian Stimulation Is Associated With Higher Implantation Rate for Patients With Polycystic Ovary Syndrome Who Underwent
Article in Frontiers in physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.
- Efficacy of progestin-primed ovarian stimulation in women with polycystic ovary syndrome undergoingFrontiers in endocrinology · 2023Pooled it
- An early LH surge may jeopardize ART outcomes of patients with PCOS and its predictive models.Reproduction & fertility · 2026Article
- A prospective cohort study on progestin-primed ovarian stimulation vs. GnRH antagonist in IVF-ICSI cycles: effects on clinical pregnancy and neonatal outcomes.Journal of ovarian research · 2025Article
- Study on the relationship between endometrial thickness on the hCG day in the progestin-primed ovarian stimulation protocol and pregnancy outcomes in frozen-thawed embryo transfer cycles.Frontiers in endocrinology · 2025Article
- Microbiota and Gut-Liver Axis: An Unbreakable Bond?Current microbiology · 2024Review
- Decay of Skin-Specific Gene Modules in Pangolins.Journal of molecular evolution · 2023Article
- Intramuscular mitochondrial and lipid metabolic changes of rats after regular high-intensity interval training (HIIT) of different training periods.Molecular biology reports · 2023Article
- The comparison between fixed versus degressive doses of medroxyprogesterone acetate combined with letrozole in patients of progestin-primed ovarian stimulation protocol: a propensity score-matched study.Frontiers in endocrinology · 2023Article
- Letrozole cotreatment with progestin-primed ovarian stimulation in women with polycystic ovary syndrome undergoing IVF treatment.Frontiers in physiology · 2022Article
Corrections and comments
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Authors and funding
14 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMany studies have demonstrated the positive clinical value of progestin-primed ovarian stimulation (PPOS) in patients with polycystic ovary syndrome (PCOS) who underwent assisted reproductive technology. However, the underlying factors contributing to this phenomenon remain unclear. We conducted a retrospective observational study to compare the clinical outcomes of women with PCOS who underwent PPOS or the short protocol to identify possible factors that influence the outcome.
methodsThis study included 304 patients who underwent PPOS and 152 patients who underwent short protocol from April 2014 to July 2019 after propensity-score matching. Human menopausal gonadotropin (hMG) dose, hormone profile, embryo development, and clinical outcomes of frozen-thawed embryo transfer (FET) cycles were compared. The primary outcome measure was the implantation rate. Logistic regression was performed to identify contributing factors, and receiver operating characteristic curve analysis was used to calculate the cutoff of luteinizing hormone (LH) difference ratio in clinical outcomes.
resultsCompared with the short protocol, PPOS resulted in a higher implantation rate (43.4% vs. 31.9%,
conclusionThe implantation rate was associated with the LH difference ratio during ovary stimulation in patients with PCOS. Our results provide the explanation why PPOS shows the positive clinical outcomes for patients with PCOS.
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